Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights
K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
Anti-tumor immune potentiation targets-engineered nanobiotechnologies: design principles and applications
R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2023 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …
Biomaterials for in situ cell therapy
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
Deep penetration of nanolevel drugs and micrometer-level T cells promoted by nanomotors for cancer immunochemotherapy
H Chen, T Shi, Y Wang, Z Liu, F Liu… - Journal of the …, 2021 - ACS Publications
The ability of nanomotors to promote the deep penetration of themselves and the loaded
drugs in diseased tissues has been proposed and confirmed. However, whether such …
drugs in diseased tissues has been proposed and confirmed. However, whether such …
Dual affinity to RBCs and target cells (DART) enhances both organ-and cell type-targeting of intravascular nanocarriers
LT Ferguson, ED Hood, T Shuvaeva, VV Shuvaev… - ACS …, 2022 - ACS Publications
A long-standing goal of nanomedicine is to improve a drug's benefit by loading it into a
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
Nano-drug delivery systems for T cell-based immunotherapy
T cell-based immunotherapy, which tackles T cell dysfunction and exhaustion, offers broad
promising for treating cancer. Various T cell-based immunotherapies, such as immune …
promising for treating cancer. Various T cell-based immunotherapies, such as immune …
Molecular dynamics insight of interaction between the functionalized-carbon nanotube and cancerous cell membrane in doxorubicin delivery
Background and objective: Doxorubicin (DOX) is a known anticancer drug which is widely
used in cancer therapy. Carbon nanotubes (CNTs) are among the most promising platforms …
used in cancer therapy. Carbon nanotubes (CNTs) are among the most promising platforms …
Applications of CRISPR technology in cellular immunotherapy
CRISPR technology has transformed multiple fields, including cancer and immunology.
CRISPR‐based gene editing and screening empowers direct genomic manipulation of …
CRISPR‐based gene editing and screening empowers direct genomic manipulation of …
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles
Simultaneous delivery of mRNA to multiple populations of antigen (Ag)–specific CD8+ T
cells is challenging given the diversity of peptide epitopes and polymorphism of class I major …
cells is challenging given the diversity of peptide epitopes and polymorphism of class I major …
A focus on “bio” in bio–nanoscience: the impact of biological factors on nanomaterial interactions
C Cortez‐Jugo, E Czuba‐Wojnilowicz… - Advanced …, 2021 - Wiley Online Library
Bio–nanoscience research encompasses studies on the interactions of nanomaterials with
biological structures or what is commonly referred to as the biointerface. Fundamental …
biological structures or what is commonly referred to as the biointerface. Fundamental …