We present a new model for the generation of theta rhythm of the hippocampus. We propose
that theta at CA1 involves extracellular current fluxes produced by alternating depolarizing …

The paramount feature of long-term potentiation (LTP) as a memory mechanism is its
characteristic persistence over time. Although the basic phenomenology of LTP persistence …

This book reviews how people and animals learn and how their behaviors are later changed
as a result of this learning. Nearly all of our behaviors are influenced by prior learning …

Experimental evidence suggests that the hippocampal theta rhythm plays a critical role in
learning. Previous studies have shown long-term potentiation (LTP) to be preferentially …

Our review focuses on the mechanisms which enable the late maintenance of hippocampal
long-term potentiation (LTP;> 3h), a phenomenon which is thought to underlie prolonged …

Memory is fundamentally important to everyday life, and memory loss has devastating
consequences to individuals and society. Understanding the neurophysiological and …

Learning based on hippocampal-dependent spatial navigation in female rats was assessed
at identified points in the estrous cycle corresponding to low (estrus) and high (proestrus) …

The increasing resolution of tract-tracing studies has led to the definition of segments along
the transverse axis of the hippocampal pyramidal cell layer, which may represent …

We focus on new properties of cellular and network processes of memory formation
involving 'synaptic tagging'and 'cross-tagging'during long-term potentiation (LTP) and long …

Little is known how synaptically released endogenous ACh affects hippocampal synaptic
plasticity in vivo. Here, we examined the role of cholinergic drive in the regulation of the …