[HTML][HTML] Pathophysiological aspects of alcohol metabolism in the liver
J Hyun, J Han, C Lee, M Yoon, Y Jung - International journal of molecular …, 2021 - mdpi.com
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …
[HTML][HTML] Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases
J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …
[HTML][HTML] SGLT-2 inhibitors in NAFLD: expanding their role beyond diabetes and cardioprotection
Non-alcoholic fatty liver disease (NAFLD) is an 'umbrella'term, comprising a spectrum
ranging from benign, liver steatosis to non-alcoholic steatohepatitis, liver fibrosis and …
ranging from benign, liver steatosis to non-alcoholic steatohepatitis, liver fibrosis and …
[HTML][HTML] Non-alcoholic fatty liver disease and diabetes
Non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM) are common
conditions that regularly co-exist and can act synergistically to drive adverse outcomes. The …
conditions that regularly co-exist and can act synergistically to drive adverse outcomes. The …
An overview of lipid metabolism and nonalcoholic fatty liver disease
K Pei, T Gui, D Kan, H Feng, Y Jin… - BioMed Research …, 2020 - Wiley Online Library
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …
Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies
G Musso, M Cassader, R Gambino - Nature reviews Drug discovery, 2016 - nature.com
Non-alcoholic fatty liver disease—the most common chronic liver disease—encompasses a
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …
histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) …
Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease
G Targher, CD Byrne - Nature Reviews Nephrology, 2017 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is caused by an accumulation of fat in the liver; the
condition can progress over time to increase the risk of developing cirrhosis, end-stage liver …
condition can progress over time to increase the risk of developing cirrhosis, end-stage liver …
[HTML][HTML] Worldwide flavor enhancer monosodium glutamate combined with high lipid diet provokes metabolic alterations and systemic anomalies: An overview
A Banerjee, S Mukherjee, BK Maji - Toxicology Reports, 2021 - Elsevier
In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …
activities that ultimately change their food habits. Majorities of such foods have harmful …
The role and mechanism of oxidative stress and nuclear receptors in the development of NAFLD
T Hong, Y Chen, X Li, Y Lu - Oxidative medicine and cellular …, 2021 - Wiley Online Library
The overproduction of reactive oxygen species (ROS) and consequent oxidative stress
contribute to the pathogenesis of acute and chronic liver diseases. It is now acknowledged …
contribute to the pathogenesis of acute and chronic liver diseases. It is now acknowledged …
The role of ChREBP in carbohydrate sensing and NAFLD development
M Régnier, T Carbinatti, L Parlati… - Nature Reviews …, 2023 - nature.com
Excessive sugar consumption and defective glucose sensing by hepatocytes contribute to
the development of metabolic diseases including type 2 diabetes mellitus (T2DM) and …
the development of metabolic diseases including type 2 diabetes mellitus (T2DM) and …