Spinal cord injury: pathophysiology, treatment strategies, associated challenges, and future implications
K Venkatesh, SK Ghosh, M Mullick… - Cell and tissue …, 2019 - Springer
Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …
Placenta and placental derivatives in regenerative therapies: experimental studies, history, and prospects
O Pogozhykh, V Prokopyuk, C Figueiredo… - Stem cells …, 2018 - Wiley Online Library
Placental structures, capable to persist in a genetically foreign organism, are a natural
model of allogeneic engraftment carrying a number of distinctive properties. In this review …
model of allogeneic engraftment carrying a number of distinctive properties. In this review …
Advancing spinal cord injury treatment through stem cell therapy: A comprehensive review of cell types, challenges, and emerging technologies in regenerative …
CW Zeng - International journal of molecular sciences, 2023 - mdpi.com
Spinal cord injuries (SCIs) can lead to significant neurological deficits and lifelong disability,
with far-reaching physical, psychological, and economic consequences for affected …
with far-reaching physical, psychological, and economic consequences for affected …
Therapeutic potential of stem cells for treatment of neurodegenerative diseases
H Ahmadian-Moghadam, MS Sadat-Shirazi… - Biotechnology …, 2020 - Springer
Neurodegenerative diseases are caused by a loss of neurons within the peripheral or
central nervous system. Inadequate repairability in the central nervous system and failure of …
central nervous system. Inadequate repairability in the central nervous system and failure of …
Significant transcriptomic changes are associated with differentiation of bone marrow-derived mesenchymal stem cells into neural progenitor-like cells in the presence …
Abstract Introduction Mesenchymal stem cells (MSCs) isolated from bone marrow have
different developmental origins, including neural crest. MSCs can differentiate into neural …
different developmental origins, including neural crest. MSCs can differentiate into neural …
Clinical trials using mesenchymal stem cells for spinal cord injury: Challenges in generating evidence
LT de Araújo, CT Macêdo, PKF Damasceno… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) remains an important public health problem which often causes
permanent loss of muscle strength, sensation, and function below the site of the injury …
permanent loss of muscle strength, sensation, and function below the site of the injury …
Potential role of growth factors controlled release in achieving enhanced neuronal trans-differentiation from mesenchymal stem cells for neural tissue repair and …
With an increase in the incidence of neurodegenerative diseases, a need to replace
incapable conventional methods has arisen. To overcome this burden, stem cells therapy …
incapable conventional methods has arisen. To overcome this burden, stem cells therapy …
A systematic review of mesenchymal stem cells in spinal cord injury, intervertebral disc repair and spinal fusion
Spinal surgery presents a challenge for both neurosurgery and orthopaedic surgery. Due to
the heterogeneous differentiation potential of mesenchymal stem cells, there is much …
the heterogeneous differentiation potential of mesenchymal stem cells, there is much …
Amnion-derived cells as a reliable resource for next-generation regenerative medicine
A Umezawa, A Hasegawa, M Inoue… - Placenta, 2019 - Elsevier
The placenta is composed of the amnion, chorionic plate, villous and smooth chorion,
decidua basalis, and umbilical cord. The amnion is a readily obtainable source of a large …
decidua basalis, and umbilical cord. The amnion is a readily obtainable source of a large …
Hematopoietic stem cells therapies
M Chivu-Economescu, M Rubach - Current stem cell research …, 2017 - ingentaconnect.com
Stem cell-based therapies are recognized as a new way to treat various diseases and
injuries, with a wide range of health benefits. The goal is to heal or replace diseased or …
injuries, with a wide range of health benefits. The goal is to heal or replace diseased or …