Second and outer coordination sphere effects in nitrogenase, hydrogenase, formate dehydrogenase, and CO dehydrogenase

ST Stripp, BR Duffus, V Fourmond, C Léger… - Chemical …, 2022 - ACS Publications
Gases like H2, N2, CO2, and CO are increasingly recognized as critical feedstock in “green”
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …

Hydrogenases

W Lubitz, H Ogata, O Rudiger, E Reijerse - Chemical reviews, 2014 - ACS Publications
The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

[FeFe]-and [NiFe]-hydrogenase diversity, mechanism, and maturation

JW Peters, GJ Schut, ES Boyd, DW Mulder… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Abstract The [FeFe]-and [NiFe]-hydrogenases catalyze the formal interconversion between
hydrogen and protons and electrons, possess characteristic non-protein ligands at their …

[HTML][HTML] Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine

S Ohta - Pharmacology & therapeutics, 2014 - Elsevier
Molecular hydrogen (H 2) has been accepted to be an inert and nonfunctional molecule in
our body. We have turned this concept by demonstrating that H 2 reacts with strong oxidants …

[PDF][PDF] Protein stability: a crystallographer's perspective

MC Deller, L Kong, B Rupp - Acta Crystallographica Section F …, 2016 - journals.iucr.org
Protein stability is a topic of major interest for the biotechnology, pharmaceutical and food
industries, in addition to being a daily consideration for academic researchers studying …

The catalytic cycle of [FeFe] hydrogenase: A tale of two sites

JA Birrell, P Rodriguez-Macia, EJ Reijerse… - Coordination Chemistry …, 2021 - Elsevier
Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the …

The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: Current status and perspectives

U Mueller, R Förster, M Hellmig, FU Huschmann… - The European Physical …, 2015 - Springer
For a little over a decade now, the Macromolecular Crystallography (MX) group at the
Helmholtz-Zentrum Berlin (HZB) has been operating three state-of-the-art synchrotron …

Bioenergetic constraints for conversion of syngas to biofuels in acetogenic bacteria

J Bertsch, V Müller - Biotechnology for biofuels, 2015 - Springer
Synthesis gas (syngas) is a gas mixture consisting mainly of H 2, CO, and CO 2 and can be
derived from different sources, including renewable materials like lignocellulose. The …

[HTML][HTML] [NiFe] hydrogenases: a common active site for hydrogen metabolism under diverse conditions

HS Shafaat, O Rüdiger, H Ogata, W Lubitz - Biochimica et Biophysica Acta …, 2013 - Elsevier
Hydrogenase proteins catalyze the reversible conversion of molecular hydrogen to protons
and electrons. The most abundant hydrogenases contain a [NiFe] active site; these proteins …

Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications

S Ohta - Methods in enzymology, 2015 - Elsevier
Molecular hydrogen (H 2) was believed to be inert and nonfunctional in mammalian cells.
We overturned this concept by demonstrating that H 2 reacts with highly reactive oxidants …