Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology

SU Chun-Yan, M Qian-Liang, K Rahman… - Chinese journal of …, 2015 - Elsevier
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively
applied for many years to treat various diseases, especially coronary heart diseases and …

Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions

M Ali, T Khan, K Fatima, QUA Ali, M Ovais… - Phytotherapy …, 2018 - Wiley Online Library
Insight into the hepatoprotective effects of medicinally important plants is important, both for
physicians and researchers. Main reasons for the use of herbal medicine include their lesser …

Molecular evidence of cryptotanshinone for treatment and prevention of human cancer

W Chen, Y Lu, G Chen, S Huang - Anti-Cancer Agents in …, 2013 - ingentaconnect.com
Cryptotanshinone is one of the major tanshinones isolated from the roots of the plant Salvia
miltiorrhiza Bunge (Danshen). Danshen has been widely used in traditional Chinese …

[HTML][HTML] Preventive and therapeutic role of Tanshinone ⅡA in hepatology

MJ Shi, BS Dong, WN Yang, SB Su, H Zhang - Biomedicine & …, 2019 - Elsevier
Liver diseases cause serious public health problems because of their high global
prevalence and poor long-term clinical outcomes. With its mild and broad therapeutic …

Increased phenolic acid and tanshinone production and transcriptional responses of biosynthetic genes in hairy root cultures of Salvia przewalskii Maxim. treated with …

J Li, B Li, L Luo, F Cao, B Yang, J Gao, Y Yan… - Molecular Biology …, 2020 - Springer
The purpose of this study is to reveal the impact of the plant hormone salicylic acid (SA) and
methyl jasmonate (MeJA) on the growth, effective components accumulation, and related …

Tanshinone I: Pharmacological activities, molecular mechanisms against diseases and future perspectives

L Ke, C Zhong, Z Chen, Z Zheng, S Li, B Chen, Q Wu… - Phytomedicine, 2023 - Elsevier
Abstract Background Tanshinone I (Tan I) is known as one of the important active
components in Salvia miltiorrhiza. In recent years, Tan I has received a substantial amount …

[HTML][HTML] Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug

H Li, P Hu, Y Zou, L Yuan, Y Xu, X Zhang, X Luo… - Frontiers in …, 2023 - frontiersin.org
Because of its high prevalence and poor long-term clinical treatment effect, liver disease is
regarded as a major public health problem around the world. Among them, viral hepatitis …

[HTML][HTML] Cryptotanshinone reverses cisplatin resistance of human lung carcinoma A549 cells through down-regulating Nrf2 pathway

C Xia, X Bai, X Hou, X Gou, Y Wang, H Zeng… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: To explore whether Nrf2 was associated with drug-resistance in cisplatin
resistant A549 (A549/DDP) cells, and if cryptotanshinone (CTS), one of the bioactive …

Tanshinone IIA attenuates contrast-induced nephropathy via Nrf2 activation in rats

R Liang, Q Zhao, G Jian, D Cheng, N Wang… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Tanshinone IIA is a chemical compound extracted from Salvia
miltiorrhiza Bunge, a perennial plant also known as red sage used in traditional Chinese …

Cryptotanshinone inhibits STAT3 signaling to alleviate cardiac fibrosis in type 1‐like diabetic rats

SH Lo, CT Hsu, HS Niu, CS Niu… - Phytotherapy …, 2017 - Wiley Online Library
Cryptotanshinone is an active principal ingredient isolated from Salvia miltiorrhiza
(Danshen), a medicinal plant used in China to treat cardiac disorders. The objective of this …