The fundamental role played by neutrophils for an efficient, acute inflammatory response
has long been appreciated, with the underlying molecular and cellular mechanisms largely …

Annexins are Ca2+ and phospholipid binding proteins forming an evolutionary conserved
multigene family with members of the family being expressed throughout animal and plant …

Glucocorticoids are widely used for the management of inflammatory diseases. Their clinical
application stems from our understanding of the inhibitory effect of the corticosteroid …

Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

Annexin A1 is a 37 kDa phospholipid-binding protein that is expressed in many tissues and
cell types, including leukocytes, lymphocytes and epithelial cells. Although Annexin A1 has …

Annexin A1 (ANXA1) has long been classed as an anti-inflammatory protein due to its
control over leukocyte-mediated immune responses. However, it is now recognized that …

Polymorphonuclear leukocyte (PMN)–derived microparticles display inhibitory properties on
target cells as assessed in vitro; since PMNs contain abundant amounts of the endogenous …

Annexin A1 (ANXA1) is a Ca2+-regulated phospholipid-binding protein involved in various
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …

Background and Purpose Butyrate has shown benefits in inflammatory bowel diseases.
However, it is not often administered orally because of its rancid smell and unpleasant taste …

Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates
(some of the) anti-inflammatory effects of glucocorticoids. Subsequently, the role of ANXA1 …