Mining and analysis of adverse drug reactions associated with perampanel based on FAERS database

P Liu, Y Zhang, X Xu, M Zhou, Y Fei, L Zhang - Epilepsy & Behavior, 2023 - Elsevier
Introduction Perampanel (PER) is a non-competitive AMPA glutamate receptor antagonist
used as an anti-seizure medication. Large post-marketing databases are still lacking for …

A lipophilic chitosan-modified self-nanoemulsifying system influencing cellular membrane metabolism enhances antibacterial and anti-biofilm efficacy for multi-drug …

D Cai, ZL Zhang, Z Feng, J Song, X Zeng, Y Tu… - Biomaterials …, 2022 - Elsevier
Wound infections, especially infections with multidrug-resistant bacteria, are a serious public
health issue worldwide. In addition, the accumulation microbial biofilm of multidrug-resistant …

Effects of the AMPAR Antagonist, Perampanel, on Cognitive Function in Rats Exposed to Neonatal Iron Overload

J da Silva, LO de Souza, MPA Severo… - Molecular …, 2024 - Springer
Iron accumulation has been associated with the pathogenesis of neurodegenerative
diseases and memory decline. As previously described by our research group, iron overload …

吡仑帕奈在癫痫共病治疗中的研究进展

陈思蕊, 李军强, 党小利… - 中国临床药理学与治疗 …, 2024 - manu41.magtech.com.cn
睡眠障碍, 偏头痛, 认知与行为障碍和焦虑抑郁等都是常见的癫痫共病, 癫痫患者的共病率是一般
人群的8 倍, 影响癫痫患者的预后和生活质量. 吡仑帕奈(perampanel, PER) …

Progress in researches for perampanel in the treatment of comorbidities of epilepsy

S CHEN, J LI, X DANG… - Chinese Journal of …, 2024 - manu41.magtech.com.cn
Sleep disorder, migraine, cognitive and behavioral disorders, anxiety and depression are
common comorbidities of epilepsy. The comorbidity rate of epilepsy patients is eight times …

Efeito do uso de perampanel na capacidade cognitiva de ratos Wistar submetidos à sobrecarga de ferro no período neonatal

JAC Silva - 2024 - lume.ufrgs.br
No decorrer da vida, diversos insultos independentes interagem e resultam em lesões
subsequentes de DNA e apoptose celular no Sistema Nervoso Central. Na composição de …