Structural diversity, bioactivities, and biosynthesis of natural diterpenoid alkaloids
Y Shen, WJ Liang, YN Shi, EJ Kennelly… - Natural Product …, 2020 - pubs.rsc.org
Covering: 2009 to 2018. Diterpenoid alkaloids, originating from the amination of natural
tetracyclic diterpenes, are a diverse class of compounds having complex structural features …
tetracyclic diterpenes, are a diverse class of compounds having complex structural features …
Classification, toxicity and bioactivity of natural diterpenoid alkaloids
Diterpenoid alkaloids are natural compounds having complex structural features with many
stereo-centres originating from the amination of natural tetracyclic diterpenes and produced …
stereo-centres originating from the amination of natural tetracyclic diterpenes and produced …
The diterpenoid alkaloids
XY Liu, BW Ke, Y Qin, FP Wang - The alkaloids: chemistry and biology, 2022 - Elsevier
The diterpenoid alkaloids are a family of extremely important natural products that have long
been a research hotspot due to their myriad of intricate structures and diverse biological …
been a research hotspot due to their myriad of intricate structures and diverse biological …
A systematic review of pharmacological activities, toxicological mechanisms and pharmacokinetic studies on Aconitum alkaloids
MI Li, LI Yu-Chen, SUN Meng-Ru, PL Zhang… - Chinese Journal of …, 2021 - Elsevier
The tubers and roots of Aconitum (Ranunculaceae) are widely used as heart medicine or
analgesic agents for the treatment of coronary heart disease, chronic heart failure …
analgesic agents for the treatment of coronary heart disease, chronic heart failure …
Phytochemicals in anticancer drug development
R Dutt, V Garg, N Khatri… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: In spite of major technological advances in conventional therapies, cancer
continues to remain the leading cause of mortality worldwide. Phytochemicals are gradually …
continues to remain the leading cause of mortality worldwide. Phytochemicals are gradually …
Anticancer Activities of C18-, C19-, C20-, and Bis-Diterpenoid Alkaloids Derived from Genus Aconitum
MY Ren, QT Yu, CY Shi, JB Luo - Molecules, 2017 - mdpi.com
Cancer is one of the most common lethal diseases, and natural products have been
extensively studied as anticancer agents considering their availability, low toxicity, and …
extensively studied as anticancer agents considering their availability, low toxicity, and …
Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
X Liang, Y Gao, S Luan - RSC advances, 2018 - pubs.rsc.org
The important pharmacological activities and structural complexity of diterpenoid alkaloids
have long stimulated strong scientific interest; some of these naturally abundant compounds …
have long stimulated strong scientific interest; some of these naturally abundant compounds …
Diterpenoid alkaloids from the root of Aconitum sinchiangense WT Wang with their antitumor and antibacterial activities
X Liang, L Chen, L Song, W Fei, M He… - Natural Product …, 2017 - Taylor & Francis
A phytochemical study of the root barks of Aconitum sinchiangense WT Wang, a traditional
Chinese herb medicine, led to the isolation of 15 diterpenoid alkaloids, including one new …
Chinese herb medicine, led to the isolation of 15 diterpenoid alkaloids, including one new …
Synthesis of structurally diverse derivatives of aconitine-type diterpenoid alkaloids and their anti-proliferative effects on canine breast cancer cells
L Zhang, Y Xie, X Liang, L Yin, C He, Z Yin, G Yue… - Bioorganic …, 2023 - Elsevier
As one of the most common malignancies in female dogs, no drugs have been developed
specifically for the treatment of canine mammary carcinoma. In our previous study, a series …
specifically for the treatment of canine mammary carcinoma. In our previous study, a series …
A new C20-diterpenoid alkaloid from the lateral roots of Aconitum carmichaeli
J Yu, TP Yin, JP Wang, RF Mei, L Cai… - Natural Product …, 2017 - Taylor & Francis
A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2–7) were
isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on …
isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on …