Advances in kinase targeting: current clinical use and clinical trials

M Rask-Andersen, J Zhang, D Fabbro… - Trends in pharmacological …, 2014 - cell.com
Phosphotransferases, also known as kinases, are the most intensively studied protein drug
target category in current pharmacological research, as evidenced by the vast number of …

Pharmaceutical implants: Classification, limitations and therapeutic applications

Z Mohtashami, Z Esmaili, MA Vakilinezhad… - Pharmaceutical …, 2020 - Taylor & Francis
Controlled/sustained delivery systems have been developed rapidly which show the ability
to overcome the obstacles of traditional delivery systems. Daily development of biomedical …

Modification of hexachiral unit cell to enhance auxetic stent performance

A Asadi, D Hedayat, S Ghofrani… - Mechanics of …, 2023 - Taylor & Francis
Stents possess disadvantages such as foreshortening and dogboning. Material selection
alongside topological modifications are two main approaches to overcome these issues …

Finite element simulation and testing of cobalt-chromium stent: a parametric study on radial strength, recoil, foreshortening, and dogboning

A Kumar, N Bhatnagar - Computer Methods in Biomechanics and …, 2021 - Taylor & Francis
The effectiveness of cardiovascular stenting procedure depends on the crimping and
expansion characteristics of a stent, influenced by its design parameters. In this study, CoCr …

Polymer–Metal Composite Healthcare Materials: From Nano to Device Scale

WK Wong, CHN Lai, WY Cheng, LH Tung… - Journal of Composites …, 2022 - mdpi.com
Metals have been investigated as biomaterials for a wide range of medical applications. At
nanoscale, some metals, such as gold nanoparticles, exhibit plasmonics, which have …

Overview of cardiovascular stent designs

C McCormick - Functionalised cardiovascular stents, 2018 - Elsevier
Coronary heart disease (CHD) is the leading cause of death globally. Research over recent
decades has greatly increased understanding of the pathophysiology of this condition and …

The conical stent in coronary artery improves hemodynamics compared with the traditional cylindrical stent

Y Yu, Y Zhou, Q Ma, S Wu, Y Sun, X Liu, Y Zhao… - International journal of …, 2017 - Elsevier
Objectives This study sought to explore the efficacy of the conical stent implantation in the
coronary artery by comparing the effects of cylindrical and conical stents on wall shear stress …

Evaluation of chemical stability of polymers of XIENCE everolimus‐eluting coronary stents in vivo by pyrolysis‐gas chromatography/mass spectrometry

M Kamberi, D Pinson, S Pacetti… - … Research Part B …, 2018 - Wiley Online Library
The polymers poly (vinylidene fluoride‐co‐hexafluoropropylene)(PVDF‐HFP) and poly (n‐
butyl methacrylate)(PBMA) are employed in manufacturing the XIENCE family of coronary …

Advances in non-invasive drug delivery for atherosclerotic heart disease

RC Maranhão, ER Tavares - Expert Opinion on Drug Delivery, 2015 - Taylor & Francis
Introduction: Apart from statins, anti-platelet agents and invasive procedures, the anti-
atherosclerotic medical weaponry for coronary heart disease (CHD) is scarce and only …

Investigation of optical and biocompatible properties of polyethylene glycol-aspirin loaded commercial pure titanium for cardiovascular device applications

M Mohanta, A Thirugnanam - Journal of Polymer Engineering, 2022 - degruyter.com
This research investigates the optical and biocompatible properties of alkali-treated cpTi
immersed in aspirin and different molecular weights of polyethylene (PEG). Instrumental …