Practical recommendations of the obesity management task force of the European association for the study of obesity for the post-bariatric surgery medical …

L Busetto, D Dicker, C Azran, RL Batterham… - Obesity facts, 2018 - karger.com
Bariatric surgery is today the most effective long-term therapy for the management of
patients with severe obesity, and its use is recommended by the relevant guidelines of the …

Summary of drug therapy to treat cognitive impairment-induced obstructive sleep apnea

D He, J Chen, X Du, L Xu - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Obstructive sleep apnea (OSA) is a severe sleep disorder associated with intermittent
hypoxia and sleep fragmentation. Cognitive impairment is a signifi-cant and common OSA …

Suppression of CHOP reduces neuronal apoptosis and rescues cognitive impairment induced by intermittent hypoxia by inhibiting Bax and Bak activation

L Xu, Y Bi, Y Xu, Y Wu, X Du, Y Mou, J Chen - Neural plasticity, 2021 - Wiley Online Library
Our previous study showed that growth arrest‐and DNA damage‐inducible gene 153
(GAD153/CHOP) plays an important role in intermittent hypoxia‐(IH‐) induced apoptosis …

Sleep-disordered breathing and Alzheimer's disease: A nationwide cohort study

JE Lee, SW Yang, YJ Ju, SK Ki, KH Chun - Psychiatry research, 2019 - Elsevier
Sleep-disordered breathing (SDB) is common and can lead to significant cognitive decline,
such as Alzheimer's disease (AD). Therefore, the present study was conducted to investigate …

Attenuation of intermittent hypoxia-induced apoptosis and fibrosis in pulmonary tissues via suppression of ER stress activation

Z Shi, L Xu, H Xie, R Ouyang, Y Ke, R Zhou… - BMC Pulmonary …, 2020 - Springer
Background Obstructive sleep apnea (OSA) is associated with pulmonary fibrosis and
endothelial apoptosis in pulmonary tissues. Chronic intermittent hypoxia (IH) is considered …

Treatment of obstructive sleep apnea: choosing the best positive airway pressure device

N Freedman - Sleep medicine clinics, 2017 - sleep.theclinics.com
Treatment with positive airway pressure (PAP) remains the primary therapy for most patients
with obstructive sleep apnea (OSA), especially those with moderate to severe OSA. This …

Compliance after switching from CPAP to bilevel for patients with non-compliant OSA: big data analysis

AV Benjafield, JLD Pepin… - BMJ open …, 2019 - bmjopenrespres.bmj.com
Introduction For patients with obstructive sleep apnoea (OSA) who are initially non-
compliant with continuous (automatic) positive airway pressure (CPAP/APAP) therapy, a …

The role of reactive oxygen species in cognitive impairment associated with sleep apnea

L Xu, Y Yang, J Chen - Experimental and Therapeutic …, 2020 - spandidos-publications.com
Obstructive sleep apnea (OSA), a common breathing and sleeping disorder, is associated
with a broad range of neurocognitive difficulties. Intermittent hypoxia (IH), one major …

Severity of nocturnal hypoxia and daytime hypercapnia predicts CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome

Z Kuklisova, R Tkacova, P Joppa, E Wouters, M Sastry - Sleep Medicine, 2017 - Elsevier
Background Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease
(COPD) are independent risk factors for cardiovascular diseases. In patients with OSA and …

Positive airway pressure therapy for obstructive sleep apnea

P Weiss, M Kryger - Otolaryngologic Clinics of North America, 2016 - oto.theclinics.com
Positive Airway Pressure Therapy for Obstructive Sleep Apnea - Otolaryngologic Clinics of
North America Skip to Main Content Otolaryngologic Clinics Log in Register Log in Subscribe …