The role of peroxisome proliferator‐activated receptor γ in lipid metabolism and inflammation in atherosclerosis

X Yang, D Shang - Cell Biology International, 2023 - Wiley Online Library
Cardiovascular disease events are the result of functional and structural abnormalities in the
arteries and heart. Atherosclerosis is the main cause and pathological basis of …

Apolipoprotein E and viral infection: Risks and Mechanisms

F Chen, Q Ke, W Wei, L Cui, Y Wang - Molecular Therapy-Nucleic Acids, 2023 - cell.com
Apolipoprotein E (ApoE) is a multifunctional protein critical for lipid metabolism and
cholesterol homeostasis. In addition to being a well-known genetic determinant of both …

Sirtuin 2 deficiency aggravates ageing-induced vascular remodelling in humans and mice

Y Zhang, X Wang, XK Li, SJ Lv, HP Wang… - European Heart …, 2023 - academic.oup.com
Aims The mechanisms underlying ageing-induced vascular remodelling remain unclear.
This study investigates the role and underlying mechanisms of the cytoplasmic deacetylase …

Advances in the treatment of atherosclerosis with ligand‐modified nanocarriers

X Deng, J Wang, S Yu, S Tan, T Yu, Q Xu, N Chen… - …, 2024 - Wiley Online Library
Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to
human well‐being. Currently, existing treatments for atherosclerosis lack sufficient efficiency …

Iron metabolism and atherosclerosis

Q Guo, C Qian, ZM Qian - Trends in Endocrinology & Metabolism, 2023 - cell.com
Despite several decades of study, whether iron is involved in the development of
atherosclerosis remains a controversial and unresolved issue. Here, we focus on the up-to …

Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗ 3-Leiden. CETP mice

WIH Panhuis, M Schönke, M Modder, HE Tom… - …, 2023 - thelancet.com
Background Circadian disturbance (CD) is the consequence of a mismatch between
endogenous circadian rhythms, behaviour, and/or environmental cycles, and frequently …

Cardiovascular adverse events in chronic myeloid leukemia patients treated with nilotinib or imatinib: a systematic review, meta-analysis and integrative bioinformatics …

S Li, J He, X Zhang, Y Cai, J Liu, X Nie… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this article is to assess the risk and potential mechanisms of
cardiovascular adverse events in patients treated with nilotinib or imatinib by conducting a …

Iron and atherosclerosis: Lessons learned from rabbits relevant to human disease

B Halliwell, F Watt, R Minqin - Free Radical Biology and Medicine, 2023 - Elsevier
The role of iron in promoting atherosclerosis, and hence the cardiovascular,
neurodegenerative and other diseases that result from atherosclerosis, has been fiercely …

Multiple aspects of lymphatic dysfunction in an ApoE −/− mouse model of hypercholesterolemia

MJ Davis, JP Scallan, JA Castorena-Gonzalez… - Frontiers in …, 2023 - frontiersin.org
Introduction: Rodent models of cardiovascular disease have uncovered various types of
lymphatic vessel dysfunction that occur in association with atherosclerosis, type II diabetes …

B-and T-lymphocyte attenuator could be a new player in accelerated atherosclerosis associated with chronic kidney disease

N Dolade, S Rayego-Mateos… - Clinical …, 2023 - portlandpress.com
Background: In chronic kidney disease (CKD), cardiovascular morbi-mortality is higher than
in general population. Atherosclerotic cardiovascular disease is accelerated in CKD, but …