[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Underwater and wet adhesion strategies for hydrogels in biomedical applications

HY Yuen, HP Bei, X Zhao - Chemical Engineering Journal, 2022 - Elsevier
Hydrogel is a class of biomaterials that is widely adopted in tissue engineering due to its
versatility and biocompatibility in mimicking natural tissue properties. For these hydrogels …

Procyanidins boost the neuroprotective effect of minocycline for intracerebral haemorrhage

T Yuan, T Wang, J Zhang, S Shi, Z Gu… - Advanced Functional …, 2023 - Wiley Online Library
Poor prognosis is often expected after the treatment of intracerebral haemorrhage (ICH)
when the approach lacks effective neuroprotective interventions. Minocycline (Mino) is a …

Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications

Z Sun, D Zhu, H Zhao, J Liu, P He, X Luan, H Hu… - Journal of …, 2023 - Springer
Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to
their unique chemical, physical, and biological properties and functions. In this …

Recent trends in the development of hydrogel therapeutics for the treatment of central nervous system disorders

Q Li, X Shao, X Dai, Q Guo, B Yuan, Y Liu… - NPG Asia …, 2022 - nature.com
The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

pH-sensitive peptide hydrogels as a combination drug delivery system for cancer treatment

Y Liu, Y Ran, Y Ge, F Raza, S Li, H Zafar, Y Wu… - Pharmaceutics, 2022 - mdpi.com
Conventional antitumor chemotherapeutics generally have shortcomings in terms of
dissolubility, selectivity and drug action time, and it has been difficult to achieve high …

[HTML][HTML] Injectable hydrogels for spinal cord injury repair

H Wang, H Zhang, Z Xie, K Chen, M Ma, Y Huang… - Engineered …, 2022 - Elsevier
Spinal cord injury (SCI) often causes severe functional impairment of body, which leads to a
huge burden to the patient and the whole society. Many strategies, especially biomaterials …

Self-crosslinked chitosan/dialdehyde xanthan gum blended hypromellose hydrogel for the controlled delivery of ampicillin, minocycline and rifampicin

FA Ngwabebhoh, O Zandraa, R Patwa, N Saha… - International Journal of …, 2021 - Elsevier
The design of improved biopolymeric based hydrogel materials with high load-capacity to
serve as biocompatible drug carriers is a challenging task with vital implications in health …