[HTML][HTML] Genomic and epigenomic profile of thyroid cancer

A Acuña-Ruiz, C Carrasco-López… - Best Practice & Research …, 2023 - Elsevier
Thyroid cancer is the most common malignancy of the endocrine system, and its incidence
has been steadily increasing. Advances in sequencing have allowed analysis of the entire …

[HTML][HTML] Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis

Y Yao, X Chen, H Yang, W Chen, Y Qian, Z Yan… - Journal of Experimental …, 2019 - Springer
Background Despite a good and overall prognosis, papillary thyroid cancer (PTC) can still
affect the quality of life of many patients, and can even be life-threatening due to its …

[HTML][HTML] LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network

Y Zhang, YX Huang, DL Wang, B Yang, HY Yan… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: The forkhead box A1 (FOXA1) is a crucial transcription factor in initiation and
development of breast, lung and prostate cancer. Previous studies about the FOXA1 …

Pathological and pharmacological functions of the metabolites of polyunsaturated fatty acids mediated by cyclooxygenases, lipoxygenases, and cytochrome P450s in …

YW Meng, JY Liu - Pharmacology & Therapeutics, 2024 - Elsevier
Oxylipins have garnered increasing attention because they were consistently shown to play
pathological and/or pharmacological roles in the development of multiple cancers. Oxylipins …

[HTML][HTML] Comprehensive characterization of the alternative splicing landscape in head and neck squamous cell carcinoma reveals novel events associated with …

ZX Li, ZQ Zheng, ZH Wei, LL Zhang, F Li, L Lin… - Theranostics, 2019 - ncbi.nlm.nih.gov
Alternative splicing (AS) has emerged as a key event in tumor development and
microenvironment formation. However, comprehensive analysis of AS and its clinical …

[HTML][HTML] The circular RNA circ-Ccnb1 dissociates Ccnb1/Cdk1 complex suppressing cell invasion and tumorigenesis

L Fang, WW Du, FM Awan, J Dong, BB Yang - Cancer letters, 2019 - Elsevier
Circular RNAs represent a large class of non-coding RNAs that are extensively expressed in
mammals. However, the functions of circular RNAs are largely unknown. We recently …

Genomic landscape of metastatic papillary thyroid carcinoma and novel biomarkers for predicting distant metastasis

X Lan, H Bao, X Ge, J Cao, X Fan, Q Zhang… - Cancer …, 2020 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland, with
a relatively high cure rate. Distant metastasis (DM) of PTC is uncommon, but when it occurs …

[HTML][HTML] A novel preclinical in vitro 3D model of oral carcinogenesis for biomarker discovery and drug testing

RT Chitturi Suryaprakash, K Shearston… - International Journal of …, 2023 - mdpi.com
This study aimed to develop an in vitro three-dimensional (3D) cell culture model of oral
carcinogenesis for the rapid, scalable testing of chemotherapeutic agents. Spheroids of …

[HTML][HTML] CircRNA circ_0067934 overexpression correlates with poor prognosis and promotes thyroid carcinoma progression

H Wang, X Yan, H Zhang, X Zhan - Medical science monitor …, 2019 - ncbi.nlm.nih.gov
Background Circular RNAs are important regulators in human cancers, including thyroid
carcinoma. The circ_0067934 RNA is reported to participate in hepatocellular carcinoma …

[HTML][HTML] PSMA expression level predicts differentiated thyroid cancer aggressiveness and patient outcome

M Sollini, L di Tommaso, M Kirienko, C Piombo… - EJNMMI research, 2019 - Springer
Background Prostate-specific membrane antigen (PSMA) is overexpressed on the
endothelial cells of tumor neo-vessels of several solid malignancies, including differentiated …