NF-κB and cell-cycle regulation: the cyclin connection

D Joyce, C Albanese, J Steer, M Fu… - Cytokine & growth factor …, 2001 - Elsevier
The cyclins are a family of proteins that are centrally involved in cell cycle regulation and
which are structurally identified by conserved “cyclin box” regions. They are regulatory …

[HTML][HTML] Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

I Azran, Y Schavinsky-Khrapunsky, M Aboud - Retrovirology, 2004 - Springer
HTLV-1 is the etiological agent of adult T-cell leukemia (ATL), the neurological syndrome
TSP/HAM and certain other clinical disorders. The viral Tax protein is considered to play a …

[HTML][HTML] The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity

J Basbous, C Arpin, G Gaudray, M Piechaczyk… - Journal of Biological …, 2003 - ASBMB
The human T-cell leukemia virus type I (HTLV-I)-encoded Tax protein activates transcription
from the viral promoter via association with the cellular basic leucine zipper factor cAMP …

Reovirus-induced apoptosis requires activation of transcription factor NF-κB

JL Connolly, SE Rodgers, P Clarke, DW Ballard… - Journal of …, 2000 - Am Soc Microbiol
Reovirus infection induces apoptosis in cultured cells and in vivo. To identify host cell factors
that mediate this response, we investigated whether reovirus infection alters the activation …

[HTML][HTML] Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation

KT Jeang, C Giam, F Majone, M Aboud - Journal of Biological Chemistry, 2004 - ASBMB
Human T-cell leukemia virus type I (HTLV-I) 1 causes adult T-cell leukemia (ATL)(1–3). The
virus is also associated with a neuropathy/myelopathy termed HTLV-associated myelopathy …

HBZ interacts with JunD and stimulates its transcriptional activity

S Thébault, J Basbous, P Hivin, C Devaux… - FEBS …, 2004 - Wiley Online Library
Human T‐cell leukemia virus type I (HTLV‐I) bZIP factor (HBZ) is a viral basic leucine zipper
protein that was originally described as a partner of cAMP response element binding protein …

Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo

JT Bartoe, B Albrecht, ND Collins, MD Robek… - Journal of …, 2000 - Am Soc Microbiol
Human T-lymphotropic virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma and is
associated with a variety of immune-mediated disorders. The role of four open reading …

Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits

VW Valeri, A Hryniewicz, V Andresen… - Blood, The Journal …, 2010 - ashpublications.org
The identification of the genes necessary for human T-cell leukemia virus (HTLV-1)
persistence in humans may provide targets for therapeutic approaches. We demonstrate that …

Autocrine antiapoptotic stimulation of cultured adult T-cell leukemia cells by overexpression of the chemokine I-309

T Ruckes, D Saul, J Van Snick… - Blood, The Journal …, 2001 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive malignancy of CD4+ T cells caused by the
human T-cell leukemia virus type 1 (HTLV-1). The viral leukemogenesis is critically …

[HTML][HTML] Human T lymphotropic virus type I (HTLV-I) oncogenesis: molecular aspects of virus and host interactions in pathogenesis of adult T cell leukemia/lymphoma …

SA Ghezeldasht, A Shirdel… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
The study of tumor viruses paves the way for understanding the mechanisms of virus
pathogenesis, including those involved in establishing infection and dissemination in the …