Clinical studies on the supplementation of manufactured human milk oligosaccharides: a systematic review

YB Schönknecht, MV Moreno Tovar, SR Jensen… - Nutrients, 2023 - mdpi.com
Human milk oligosaccharides (HMOs) are a major component of human milk. They are
associated with multiple health benefits and are manufactured on a large scale for their …

From birth to weaning: a window of opportunity for microbiota

V Biagioli, G Volpedo, A Riva, P Mainardi, P Striano - Nutrients, 2024 - mdpi.com
(1) Background: The first 1000 days of life constitute a critical window of opportunity for
microbiota development. Nutrients play a crucial role in enriching and diversifying the …

Infant Formula Supplemented with Five Human Milk Oligosaccharides Shifts the Fecal Microbiome of Formula-Fed Infants Closer to That of Breastfed Infants

AQ Holst, P Myers, P Rodríguez-García, GDA Hermes… - Nutrients, 2023 - mdpi.com
Breastmilk is the optimal source of infant nutrition, with short-term and long-term health
benefits. Some of these benefits are mediated by human milk oligosaccharides (HMOs), a …

Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyond

C Lordan, AK Roche, D Delsing, A Nauta… - Microbiology and …, 2024 - Am Soc Microbiol
Human milk oligosaccharides (HMOs) are complex, multi-functional glycans present in
human breast milk. They represent an intricate mix of heterogeneous structures which reach …

Cluster-specific associations between the gut microbiota and behavioral outcomes in preschool-aged children

M van de Wouw, Y Wang, ML Workentine… - Microbiome, 2024 - Springer
Background The gut microbiota is recognized as a regulator of brain development and
behavioral outcomes during childhood. Nonetheless, associations between the gut …

[HTML][HTML] Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics …

EM Mercer, HR Ramay, S Moossavi… - Microbiome, 2024 - Springer
Background The gut microbiome undergoes primary ecological succession over the course
of early life before achieving ecosystem stability around 3 years of age. These maturational …

Bifidobacterium breve Protects the Intestinal Epithelium and Mitigates Inflammation in Colitis via Regulating the Gut Microbiota–Cholic Acid Pathway

Y Li, H Xu, L Zhou, Y Zhang, W Yu, S Li… - Journal of Agricultural …, 2024 - ACS Publications
In this study, we aimed to explore the protective effects of Bifidobacterium in colitis mice and
the potential mechanisms. Results showed that Bifidobacterium breve (B. breve) effectively …

Construction and efficacy evaluation of chitosan-based nanoparticles for colon-targeted release of linoleic acid in rat pups

X Wang, H Chen, B Yang, J Zhao, H Zhang… - International Journal of …, 2023 - Elsevier
Long chain fatty acids in the colon play important roles in infant development. This study
aimed to establish a colon-targeted long chain fatty acid release system in rat pups, with …

Long-term and trimester-specific effects of prenatal stress on the child gut microbiota

L Rojas, M van de Wouw, Y Wang… - …, 2023 - Elsevier
Objective Stress is common among pregnant individuals and is associated with an altered
gut microbiota composition in infants. It is unknown if these compositional changes persist …

The Role of Diet and Nutritional Interventions for the Infant Gut Microbiome

G Catassi, M Aloi, V Giorgio, A Gasbarrini… - Nutrients, 2024 - mdpi.com
The infant gut microbiome plays a key role in the healthy development of the human
organism and appears to be influenced by dietary practices through multiple pathways. First …