Mitochondria: It is all about energy

A Casanova, A Wevers, S Navarro-Ledesma… - Frontiers in …, 2023 - frontiersin.org
Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Effects of resveratrol, curcumin and quercetin supplementation on bone metabolism—a systematic review

AD Inchingolo, AM Inchingolo, G Malcangi, P Avantario… - Nutrients, 2022 - mdpi.com
Phenolic compounds are natural phytochemicals that have recently reported numerous
health benefits. Resveratrol, curcumin, and quercetin have recently received the most …

Anti-inflammatory, antioxidant, and neuroprotective effects of polyphenols—polyphenols as an element of diet therapy in depressive disorders

A Winiarska-Mieczan, M Kwiecień… - International Journal of …, 2023 - mdpi.com
Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Cellular senescence of renal tubular epithelial cells in renal fibrosis

JQ Zhang, YY Li, XY Zhang, ZH Tian, C Liu… - Frontiers in …, 2023 - frontiersin.org
Renal fibrosis (RF) is the common pathological manifestation of virtually all chronic kidney
diseases (CKD) and one of the major causes of end-stage renal disease (ESRD), but the …

Neurodegenerative diseases: Can caffeine be a powerful ally to weaken neuroinflammation?

M Ruggiero, R Calvello, C Porro, G Messina… - International Journal of …, 2022 - mdpi.com
In recent years, there has been considerable research showing that coffee consumption
seems to be beneficial to human health, as it contains a mixture of different bioactive …

Macrophage and monocyte subsets in response to ischemic stroke

N Blank‐Stein, E Mass - European Journal of Immunology, 2023 - Wiley Online Library
Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

Curcumin modulates astrocyte function under basal and inflammatory conditions

M Seady, FT Fróes, CA Gonçalves, MC Leite - Brain Research, 2023 - Elsevier
Curcumin is a pleiotropic molecule with well-known anti-inflammatory effects. This molecule
has attracted attention due to its capacity to pass the blood–brain–barrier and modulate …

Antiaging effects of dietary supplements and natural products

L Gao, X Liu, X Luo, X Lou, P Li, X Li… - Frontiers in Pharmacology, 2023 - frontiersin.org
Aging is an inevitable process influenced by genetics, lifestyles, and environments. With the
rapid social and economic development in recent decades, the proportion of the elderly has …

Effect of systemic inflammation in the CNS: a silent history of neuronal damage

MV Millán Solano, C Salinas Lara… - International Journal of …, 2023 - mdpi.com
Central nervous system (CNS) infections including meningitis and encephalitis, resulting
from the blood-borne spread of specific microorganisms, provoke nervous tissue damage …