[HTML][HTML] Radiation-induced lung toxicity–cellular and molecular mechanisms of pathogenesis, management, and literature review

L Käsmann, A Dietrich, CA Staab-Weijnitz… - Radiation …, 2020 - Springer
Lung, breast, and esophageal cancer represent three common malignancies with high
incidence and mortality worldwide. The management of these tumors critically relies on …

[HTML][HTML] Differentiation of COVID-19 pneumonitis and ICI induced pneumonitis

DW Dumoulin, HA Gietema, MS Paats… - Frontiers in …, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICI) have become the standard of care treatment for several
tumor types. ICI-induced pneumonitis is a serious complication seen with treatment with …

[HTML][HTML] Phase II study of high-dose [131I] metaiodobenzylguanidine therapy for patients with metastatic pheochromocytoma and paraganglioma

S Gonias, R Goldsby, KK Matthay… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Purpose To evaluate the safety and efficacy of high-dose [131 I] metaiodobenzylguanidine
([131 I] MIBG) in the treatment of malignant pheochromocytoma (PHEO) and paraganglioma …

Pulmonary changes after radiotherapy for conservative treatment of breast cancer: a prospective study

M Krengli, M Sacco, G Loi, L Masini, D Ferrante… - International Journal of …, 2008 - Elsevier
PURPOSE: Radiotherapy (RT) after conservative surgery for breast cancer involves part of
the pulmonary parenchyma with a potential detrimental effect of reducing the normal …

Metformin attenuates radiation-induced pulmonary fibrosis in a murine model

J Wang, Y Wang, J Han, H Mei, D Yu… - Radiation …, 2017 - meridian.allenpress.com
While radiotherapy continues to be a major cancer treatment option, its dose-limiting side
effects, such as pulmonary fibrosis, severely impair the quality of life in these patients. In this …

[HTML][HTML] Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis

J Wang, F Zhou, Z Li, H Mei, Y Wang, H Ma, L Shi… - Scientific Reports, 2018 - nature.com
Radiation-induced lung injury has restricted radiotherapy for thoracic cancer. The purpose of
this study was to investigate the radioprotective effects of bromodomain and extra terminal …

Clinical and radiologic distinctions between secondary bronchiolitis obliterans organizing pneumonia and cryptogenic organizing pneumonia

TS Vasu, R Cavallazzi, A Hirani, D Sharma… - Respiratory …, 2009 - rc.rcjournal.com
BACKGROUND: Bronchiolitis obliterans organizing pneumonia (BOOP) is a distinct pattern
of reaction of the lung to injury. It may be idiopathic or secondary to a variety of injuries. The …

[HTML][HTML] Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model

M Li, A Abdollahi, HJ Gröne, KE Lipson, C Belka… - Radiation …, 2009 - Springer
Background We have previously shown that small molecule PDGF receptor tyrosine kinase
inhibitors (RTKI) can drastically attenuate radiation-induced pulmonary fibrosis if the drug …

Pathology of small airways disease

TC Allen - Archives of pathology & laboratory medicine, 2010 - meridian.allenpress.com
Context.—The term small airways disease encompasses a generally poorly understood
group of lung diseases that may arise primarily within the small airways or secondarily from …

Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer

GR Epler, EM Kelly - The Oncologist, 2014 - academic.oup.com
Background. Radiation therapy for breast cancer has been implicated in the development of
bronchiolitis obliterans organizing pneumonia (BOOP). This inflammatory lung disorder was …