[HTML][HTML] Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

[HTML][HTML] Using experimental models to decipher the effects of acetaminophen and NSAIDs on reproductive development and health

B Boizet-Bonhoure, S Déjardin, M Rossitto… - Frontiers in …, 2022 - frontiersin.org
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin (acetylsalicylic acid),
diclofenac and ibuprofen (IBU), and analgesic drugs, such as acetaminophen (APAP, or …

[HTML][HTML] Sex-specific neurobehavioral and prefrontal cortex gene expression alterations following developmental acetaminophen exposure in mice

BH Baker, EE Rafikian, PB Hamblin, MD Strait… - Neurobiology of …, 2023 - Elsevier
Abstract Acetaminophen (N-acetyl-p-aminophenol (APAP), also known as paracetamol) is
one of the most common medications used by the general population, including pregnant …

Intergenerational effects on fertility in male and female mice after chronic exposure to environmental doses of NSAIDs and 17α-ethinylestradiol mixtures

P Philibert, I Stévant, S Déjardin, M Girard… - Food and Chemical …, 2023 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) and 17α-ethinylestradiol (EE2) are
extensively used in human and veterinary medicine. Due to their partial removal by …

[HTML][HTML] Cocktails of NSAIDs and 17α Ethinylestradiol at Environmentally Relevant Doses in Drinking Water Alter Puberty Onset in Mice Intergenerationally

P Philibert, S Déjardin, M Girard, Q Durix… - International Journal of …, 2023 - mdpi.com
Non-steroidal anti-inflammatory drugs (NSAIDs) and 17α-ethinyl-estradiol (EE2) are among
the most relevant endocrine-disrupting pharmaceuticals found in the environment …

Ibuprofen-based advanced therapeutics: Breaking the inflammatory link in cancer, neurodegeneration, and diseases

A Upadhyay, A Amanullah, V Joshi… - Drug metabolism …, 2021 - Taylor & Francis
Ibuprofen is a classical nonsteroidal anti-inflammatory drug (NSAID) highly prescribed to
reduce acute pain and inflammation under an array of conditions, including rheumatoid …

[HTML][HTML] Biochemical and structural characteristics, gene regulation, physiological, pathological and clinical features of lipocalin-type prostaglandin D2 synthase as a …

Y Urade - Frontiers in Physiology, 2021 - frontiersin.org
Lipocalin-type prostaglandin (PG) D 2 synthase (L-PGDS) catalyzes the isomerization of
PGH 2, a common precursor of the two series of PGs, to produce PGD 2. PGD 2 stimulates …

Pharmacotherapy during pregnancy: An endodontic perspective

A Ather, S Zhong, AJ Rosenbaum, RB Quinonez… - Journal of …, 2020 - Elsevier
Odontogenic pain affects up to 54.9% of pregnant women 1, 2, 3. This pain is often
associated with pulpal and/or periapical infections that pose risks to women and their fetus …

Early-life long-term ibuprofen exposure reduces reproductive capacity involved in spermatogenesis impairment and associated with the transcription factor DAF-5 in …

CW Yu, PL Yen, CM How, YH Kuo, VHC Liao - Chemosphere, 2024 - Elsevier
Pharmaceuticals and personal care products (PPCPs) are emerging environmental
contaminants and have raised significant concern due to their potential adverse impact on …

In-depth study of adsorption mechanisms and interactions in the removal of pharmaceutical contaminants via activated carbon: a physicochemical analysis

R Ghorbali, L Sellaoui, H Ghalla… - … Science and Pollution …, 2024 - Springer
This study presents a theoretical analysis of the adsorption process of pharmaceutical
pollutants, specifically acetaminophen (ATP) and diclofenac (DFC), onto activated carbon …