[HTML][HTML] Pyroptosis: A new frontier in cancer
Y Fang, S Tian, Y Pan, W Li, Q Wang, Y Tang… - Biomedicine & …, 2020 - Elsevier
Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …
[HTML][HTML] Esophageal cancer: Epidemiology, risk factors and screening
J Li, J Xu, Y Zheng, Y Gao, S He, H Li… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
More than 600,000 people are diagnosed with esophageal cancer (EC) every year globally,
and the five-year survival rate of EC is less than 20%. Two common histological subtypes of …
and the five-year survival rate of EC is less than 20%. Two common histological subtypes of …
[HTML][HTML] Beyond the stomach: an updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment
TL Testerman, J Morris - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is an extremely common, yet underappreciated, pathogen that
is able to alter host physiology and subvert the host immune response, allowing it to persist …
is able to alter host physiology and subvert the host immune response, allowing it to persist …
[HTML][HTML] Association between diabetes mellitus and gastroesophageal reflux disease: a meta-analysis
XM Sun, JC Tan, Y Zhu, L Lin - World Journal of Gastroenterology …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate whether there is a link between diabetes mellitus (DM) and
gastroesophageal reflux disease (GERD). METHODS: We conducted a systematic search of …
gastroesophageal reflux disease (GERD). METHODS: We conducted a systematic search of …
Reflux esophagitis and its role in the pathogenesis of Barrett's metaplasia
RF Souza - Journal of gastroenterology, 2017 - Springer
Reflux esophagitis damages the squamous epithelium that normally lines the esophagus,
and promotes replacement of the damaged squamous lining by the intestinal metaplasia of …
and promotes replacement of the damaged squamous lining by the intestinal metaplasia of …
[HTML][HTML] NOD-like receptor protein 3 inflammasome priming and activation in Barrett's epithelial cells
Y Nadatani, X Huo, X Zhang, C Yu, E Cheng… - Cellular and molecular …, 2016 - Elsevier
Background & Aims Microbial molecular products incite intestinal inflammation by activating
Toll-like receptors (TLRs) and inflammasomes of the innate immune system. This system's …
Toll-like receptors (TLRs) and inflammasomes of the innate immune system. This system's …
Diet and lifestyle factors and risk of subtypes of esophageal and gastric cancers: classification tree analysis
SAN Silvera, ST Mayne, MD Gammon, TL Vaughan… - Annals of …, 2014 - Elsevier
Purpose Although risk factors for squamous cell carcinoma of the esophagus and
adenocarcinomas of the esophagus (EA), gastric cardia (GC), and other (noncardia) gastric …
adenocarcinomas of the esophagus (EA), gastric cardia (GC), and other (noncardia) gastric …
A human Barrett's esophagus organoid system reveals epithelial-mesenchymal plasticity induced by acid and bile salts
Q Zhang, A Bansal, KB Dunbar… - American Journal …, 2022 - journals.physiology.org
The pathogenesis of subsquamous intestinal metaplasia (SSIM), in which glands of Barrett's
esophagus (BE) are buried under esophageal squamous epithelium, is unknown. In a rat …
esophagus (BE) are buried under esophageal squamous epithelium, is unknown. In a rat …
Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis
Objective To identify and characterise DNA methylation subtypes in oesophageal
adenocarcinoma (EAC) and its precursor Barrett's oesophagus (BE). Design We performed …
adenocarcinoma (EAC) and its precursor Barrett's oesophagus (BE). Design We performed …
Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux
CD Minacapelli, M Bajpai, X Geng… - American Journal …, 2017 - journals.physiology.org
Gastroesophageal reflux disease (GERD) clinically predisposes to columnar Barrett's
metaplasia (BM) in the distal esophagus. We demonstrate evidence supporting the cellular …
metaplasia (BM) in the distal esophagus. We demonstrate evidence supporting the cellular …