Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies

H Lu, T Hong, Y Jiang, M Whiteway, S Zhang - Advanced Drug Delivery …, 2023 - Elsevier
Candidiasis is an infection caused by fungi from a Candida species, most commonly
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …

Comprehensive Review on the Virulence Factors and Therapeutic Strategies with the Aid of Artificial Intelligence against Mucormycosis

M Tanwar, A Singh, TP Singh, S Sharma… - ACS Infectious …, 2024 - ACS Publications
Mucormycosis, a rare but deadly fungal infection, was an epidemic during the COVID-19
pandemic. The rise in cases (COVID-19-associated mucormycosis, CAM) is attributed to …

Candida albicans overgrowth disrupts the gut microbiota in mice bearing oral cancer

X Wang, S Wu, L Li, Z Yan - Mycology, 2024 - Taylor & Francis
Candida albicans is one of the most common opportunistic fungi in cancer patients. This
study explored the influence of C. albicans on gut microbiota in oral tumour-bearing mice by …

Burden of fungal infections in Kenya

SN Ratemo, DW Denning - Mycology, 2023 - Taylor & Francis
The burden of fungal infections has been on the rise globally and remains a significant
public health concern in Kenya. We estimated the incidence and prevalence of fungal …

Pleiotropic functions of SscA on the asexual spore of the human pathogenic fungus Aspergillus fumigatus

YE Son, J Han, KT Lee, HS Park - Mycology, 2024 - Taylor & Francis
Asexual spores, called conidia, are key reproductive fungal particles that enable survival in
harsh environmental conditions or host systems. The conidia can infect humans, animals …

Cyclic Tetrapeptides with Synergistic Antifungal Activity from the Fungus Aspergillus westerdijkiae Using LC-MS/MS-Based Molecular Networking

J Han, H Wang, R Zhang, H Dai, B Chen, T Wang… - Antibiotics, 2022 - mdpi.com
Fungal natural products play a prominent role in the development of pharmaceuticalagents.
Two new cyclic tetrapeptides (CTPs), westertide A (1) and B (2), with eight known …

Typing of Candida spp. from Colonized COVID-19 Patients Reveal Virulent Genetic Backgrounds and Clonal Dispersion

E Quiroga-Vargas, MÁ Loyola-Cruz, A Rojas-Bernabé… - Pathogens, 2023 - mdpi.com
Advances in the knowledge of the pathogenesis of SARS-CoV-2 allowed the survival of
COVID-19 patients in intensive care units. However, due to the clinical characteristics of …

Construction of Candida albicans Adhesin-Exposed Synthetic Cells for Preventing Systemic Fungal Infection

Z Zhao, Y Sun, M Li, Q Yu - Vaccines, 2023 - mdpi.com
The development of efficient fungal vaccines is urgent for preventing life-threatening
systemic fungal infections. In this study, we prepared a synthetic, cell-based fungal vaccine …

Riverine mycobiome dynamics: From South African tributaries to laboratory bioreactors

K Smith, W Stone, A Botha, H Steffen, G Wolfaardt - Mycology, 2024 - Taylor & Francis
Riverine fungi have the capacity for both pathogenicity, pertinent for countries with elevated
immunosuppressed individuals, and bioremediation potential. The purpose was (i) to screen …

Fibronectin-binding molecules of Scedosporium apiospermum: focus on adhesive events

ALS Santos, BA Silva, MML da Cunha… - Brazilian Journal of …, 2023 - Springer
Scedosporium apiospermum is a widespread, emerging, and multidrug-resistant
filamentous fungus that can cause localized and disseminated infections. The initial step in …