The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …

The syndrome of cerebellar ataxia with neuropathy and bilateral vestibular areflexia
(CANVAS) has emerged progressively during the last 30 years. It was first outlined by the …

Amyotrophic lateral sclerosis is a relentlessly progressive multi-system condition. The
clinical picture is dominated by upper and lower motor neuron degeneration, but extra-motor …

Depression is the leading cause of physiological problems and suicide. Previous studies
have indicated that individuals with depression show abnormal processing of both positive …

Objective Increasing evidence suggests that cerebellar damage impacts on cognitive
functions. Frontotemporal dementias (FTDs) are neurodegenerative brain conditions …

Integrating independent but converging lines of research on brain function and
neurodevelopment across scales, this article proposes that serotonin 2A receptor (5-HT2AR) …

Treadmill training (TT) has been extensively used as an intervention to improve gait and
mobility in patients with Parkinson's disease (PD). Regional and global effects on brain …

The role of the cerebellum in cognitive function has been broadly investigated in the last
decades from an anatomical, clinical, and functional point of view and new evidence points …

Recent findings challenge the prior notion that the cerebellum remains unaffected by
Alzheimer's disease (AD). Yet, it is unclear whether AD exacerbates age-related cerebellar …

Background: Parkinson's disease (PD) results in both motor and non-motor symptoms.
Traditionally, the underlying mechanism of PD has been linked to neurodegeneration of the …