[HTML][HTML] Reprogramming neurons for regeneration: The fountain of youth

SG Yang, XW Wang, C Qian, FQ Zhou - Progress in neurobiology, 2022 - Elsevier
Neurons in the central nervous system (CNS) are terminally differentiated cells that
gradually lose their ability to support regeneration during maturation due to changes in …

[HTML][HTML] Krüppel-like factor-9 and Krüppel-like factor-13: highly related, multi-functional, transcriptional repressors and activators of oncogenesis

FA Simmen, I Alhallak, RCM Simmen - Cancers, 2023 - mdpi.com
Simple Summary Krüppel-like Factor-9 (KLF9) and Krüppel-like Factor-13 (KLF13) are
highly related proteins that function as inducers and/or repressors of specific target gene …

[HTML][HTML] Genetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury

C Zhou, P Sun, MH Hamblin, KJ Yin - Journal of Neuroinflammation, 2022 - Springer
Background The long-term functional recovery of traumatic brain injury (TBI) is hampered by
pathological events, such as parenchymal neuroinflammation, neuronal death, and white …

[HTML][HTML] KLF13 Regulates the Activity of the GH-Induced JAK/STAT Signaling by Targeting Genes Involved in the Pathway

J Ávila-Mendoza, K Delgado-Rueda… - International Journal of …, 2023 - mdpi.com
The Krüppel-like factor 13 (KLF13) has emerged as an important transcription factor
involved in essential processes of the central nervous system (CNS). It predominantly …

[HTML][HTML] Structural variation and eQTL analysis in two experimental populations of chickens divergently selected for feather-pecking behavior

C Falker-Gieske, J Bennewitz, J Tetens - neurogenetics, 2023 - Springer
Feather pecking (FP) is a damaging nonaggressive behavior in laying hens with a heritable
component. Its occurrence has been linked to the immune system, the circadian clock, and …

[HTML][HTML] Interaction Between the Intestinal Microbial Community and Transcriptome Profile in Common Carp (Cyprinus carpio L.)

S Su, X Jing, C Zhang, Y Hou, Z Li, X Yang… - Frontiers in …, 2021 - frontiersin.org
In a previous study, we found that the growth performance of the new strain of Huanghe carp
is related to gene expression and bacterial community in the gut. In order to better …

Identification of regeneration and hub genes and pathways at different time points after spinal cord injury

S Fang, L Zhong, A Wang, H Zhang, ZS Yin - Molecular Neurobiology, 2021 - Springer
Spinal cord injury (SCI) is a neurological injury that can cause neuronal loss around the
lesion site and leads to locomotive and sensory deficits. However, the underlying molecular …

[HTML][HTML] Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation

M Minto, JE Sotelo-Fonseca, V Ramesh, AE West - bioRxiv, 2024 - ncbi.nlm.nih.gov
Background: The Zic family of transcription factors (TFs) promote both proliferation and
maturation of cerebellar granule neurons (CGNs), raising the question of how a single …

[HTML][HTML] Moving CNS axon growth and regeneration research into human model systems

BP Lear, DL Moore - Frontiers in Neuroscience, 2023 - frontiersin.org
Axon regeneration is limited in the adult mammalian central nervous system (CNS) due to
both intrinsic and extrinsic factors. Rodent studies have shown that developmental age can …

RNA-seq analysis reveals potential molecular mechanisms of ZNF580/ZFP580 promoting neuronal survival and inhibiting apoptosis after hypoxic-ischemic brain …

C Yin, Y Ji, N Ma, K Chen, W Zhang, D Bai, X Jia, S Xia… - Neuroscience, 2022 - Elsevier
Neonatal hypoxic-ischemic brain damage (HIBD) is one of the main causes of neonatal
acute death and chronic nervous system impairment, but still lacks effective treatments …