Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

Transport and interactions of nanoparticles in the kidneys

B Du, M Yu, J Zheng - Nature Reviews Materials, 2018 - nature.com
Kidneys are a major organ for blood filtration and waste elimination and thus play a key role
in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with …

Mesoporous silica nanoparticles for drug delivery: Current insights

M Vallet-Regí, M Colilla, I Izquierdo-Barba, M Manzano - Molecules, 2017 - mdpi.com
This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug
delivery systems. Their intrinsic structural, textural and chemical features permit to design …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Mesoporous silica nanoparticles in drug delivery and biomedical applications

Y Wang, Q Zhao, N Han, L Bai, J Li, J Liu, E Che… - … , Biology and Medicine, 2015 - Elsevier
In the past decade, mesoporous silica nanoparticles (MSNs) with a large surface area and
pore volume have attracted considerable attention for their application in drug delivery and …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

[HTML][HTML] A review on the latest developments of mesoporous silica nanoparticles as a promising platform for diagnosis and treatment of cancer

F Ahmadi, A Sodagar-Taleghani… - International Journal of …, 2022 - Elsevier
Cancer is the second cause of human mortality after cardiovascular disease around the
globe. Conventional cancer therapies are chemotherapy, radiation, and surgery. In fact, due …

Sol–gel‐based advanced porous silica materials for biomedical applications

Q Lei, J Guo, A Noureddine, A Wang… - Advanced Functional …, 2020 - Wiley Online Library
Porous silica‐based materials have burgeoning applications ranging from fillers and
additives, to adsorbents, catalysts, and recently therapeutic agents and vaccines in …

Tumor targeting strategies of smart fluorescent nanoparticles and their applications in cancer diagnosis and treatment

J He, C Li, L Ding, Y Huang, X Yin, J Zhang… - Advanced …, 2019 - Wiley Online Library
Advantages such as strong signal strength, resistance to photobleaching, tunable
fluorescence emissions, high sensitivity, and biocompatibility are the driving forces for the …