Introduction Inflammation is a defensive response of the organism to irritation which is
manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response …

Iron, as an essential trace element for the organism, is vital for maintaining the organism's
health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus …

Oxidative stress and intestinal inflammation are main pathological features of ulcerative
colitis (UC). Ferroptosis, characterized by iron accumulation and lipid peroxidation, is closely …

Background. Ferroptosis, a newly discovered mode of cell death, emerges as a new target
for atherosclerosis (AS). Long noncoding RNAs (lncRNAs) are involved in the regulation of …

Astaxanthin, a red-orange liposoluble carotenoid, has been the centre of considerable
attention in recent years for its numerous biological activities, notably its potent antioxidant …

Triphenyl phosphate (TPhP) serves as a major organophosphorus flame retardant, and its
induced neurodevelopmental toxicity has attracted widespread attention, but the mechanism …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is considered a
“multisystem” disease that simultaneously suffers from metabolic diseases and hepatic …

Endometritis is an inflammatory condition that affects the endometrium; it is induced by
bacterial infection and often leads to infertility and repeated abortions. Farnesoid X receptor …

Sepsis is a heterogenous syndrome with concurrent hyperinflammation and immune
suppression. A prominent feature of immunosuppression during sepsis is the dysfunction …

Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly
characterized by the destruction of articular cartilage. Owing to its native avascular property …