Advanced synthetic strategies for constructing quinazolinone scaffolds

RS Rohokale, UA Kshirsagar - Synthesis, 2016 - thieme-connect.com
Quinazolinones are important heterocyclic scaffolds because of their broad spectrum of
medicinal and pharmacological properties. The development of advanced synthetic …

Solvent-free, mechanochemically scalable synthesis of 2, 3-dihydroquinazolin-4 (1H)-one using Brønsted acid catalyst

G Yashwantrao, VP Jejurkar, R Kshatriya… - ACS Sustainable …, 2019 - ACS Publications
Although the synthesis of novel N-heterocyclic molecules is extremely demanding as well as
challenging, the involvement of toxic solvents often triggers environmental safety concerns …

[HTML][HTML] Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects

S Gulati, SE John… - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …

Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones

SK Singh, S Kumar, MS Yadav… - The Journal of Organic …, 2022 - ACS Publications
The glycosyl 1, 2, 3-triazoles are expediently accessible from readily available sugar-
derived glycosyl azide by utilizing modular CuAAC “Click Chemistry”, and the resulting …

Enantioselective copper‐catalyzed borylative cyclization for the synthesis of quinazolinones

Q Dherbassy, S Manna, C Shi… - Angewandte …, 2021 - Wiley Online Library
Quinazolinones are common substructures in molecules of medicinal importance. We report
an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged …

Recent Development in Palladium-Catalyzed Domino Reactions: Access to Materials and Biologically Important Carbo-and Heterocycles

HA Dondas, MG Retamosa, JM Sansano - Organometallics, 2019 - ACS Publications
The chemistry of palladium complexes has no limits. Many domino processes (even
multicomponent) are continuously appearing in the literature. Carbocyclic and heterocyclic …

Catalytic asymmetric construction of the tryptanthrin skeleton via an enantioselective decarboxylative [4+ 2] cyclization

GJ Mei, CY Bian, GH Li, SL Xu, WQ Zheng, F Shi - Organic letters, 2017 - ACS Publications
The first catalytic asymmetric construction of the tryptanthrin skeleton has been established,
taking advantage of a palladium (0)/chiral ligand-catalyzed enantioselective decarboxylative …

Chemistry of the fumiquinazolines and structurally related alkaloids

DISP Resende, P Boonpothong, E Sousa… - Natural product …, 2019 - pubs.rsc.org
Covering: this review covers the literature from 1992 to 2018 To date, approximately 80
naturally-occurring secondary metabolites which are structurally-related to fumiquinazolines …

Synthesis of pyrido-fused quinazolinone derivatives via copper-catalyzed domino reaction

M Liu, M Shu, C Yao, G Yin, D Wang, J Huang - Organic letters, 2016 - ACS Publications
A simple and efficient synthesis of 11 H-pyrido [2, 1-b] quinazolin-11-ones by Cu (OAc) 2·
H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine …

[HTML][HTML] Microwave-assisted synthesis of quinazolines and quinazolinones: an overview

L Mohammadkhani, MM Heravi - Frontiers in chemistry, 2020 - frontiersin.org
Microwave irradiation (MWI), as a unique, effective, sustainable, more economic, and
greener source of energy compared to conventional heating, is applied in different organic …