Recent advances and prospects in the organocatalytic synthesis of quinazolinones

B Borah, S Swain, M Patat, LR Chowhan - Frontiers in Chemistry, 2022 - frontiersin.org
Quinazolinone, a bicyclic compound, comprises a pyrimidine ring fused at 4´ and 8´
positions with a benzene ring and constitutes a substantial class of nitrogen-containing …

Cp* Co III-catalyzed formal [4+ 2] cycloaddition of benzamides to afford quinazolinone derivatives

J Yang, X Hu, Z Liu, X Li, Y Dong, G Liu - Chemical Communications, 2019 - pubs.rsc.org
A Cp* CoIII-catalyzed arene C–H bond amidation/annulation of benzamides was developed
to afford quinazolinone derivatives in one-pot with high yields and broad substrate scope …

Palladium-catalyzed four-component carbonylative synthesis of 2, 3-disubstituted quinazolin-4 (3H)-ones: Convenient methaqualone preparation

JB Peng, HQ Geng, W Wang, X Qi, J Ying, XF Wu - Journal of Catalysis, 2018 - Elsevier
A palladium-catalyzed four-component carbonylative cyclization reaction for the synthesis of
2, 3-disubstituted quinazolin-4 (3H)-ones has been developed. A range of different 2, 3 …

N-Methoxyamide: An Alternative Amidation Reagent in the Rhodium(III)-Catalyzed C–H Activation

C Zhou, J Zhao, W Guo, J Jiang, J Wang - Organic letters, 2019 - ACS Publications
In the field of transition-metal-catalyzed C–H activation, N-methoxyamides are widely used
as C–H activation substrate. Unexpectedly, in this work N-methoxyamides were found to …

Lewis-base boryl radicals enabled borylation, radical catalysis and reduction reactions

J Jin, H Xia, F Zhang, Y Wang - Chinese Journal of Organic …, 2020 - sioc-journal.cn
Free radical reactions represent an efficient and significant tool to construct organic
molecules by taking advantages of the high-efficiency, remarkable selectivity and good …

NHPI/O2‐Mediated Electrochemical Intermolecular Cyclization/Dehydrogenation for the Construction of Polycyclic Quinazolinones

L Liu, Z Xu, J Lin, Z Zhang, Y Wu… - Advanced Synthesis …, 2023 - Wiley Online Library
Herein, an eco‐friendly and atom‐economical electrochemical methodology with isatins and
1, 2, 3, 4‐tetrahydroisoquinolines through NHPI/O2‐mediated intermolecular …

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo [1, 2-a] quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative …

M Viji, M Vishwanath, J Sim, Y Park, C Jung, S Lee… - RSC …, 2020 - pubs.rsc.org
A metal-free and efficient procedure for the synthesis of pyrrolo [1, 2-a] quinoxalines,
quinazolinones, and indolo [1, 2-a] quinoxaline has been developed. The key features of our …

Hydrogen Atom Transfer‐Mediated Domino Cyclisation Reaction to Access (Spiro) Quinazolinones

OJ Turner, DJ Hirst, JA Murphy - Chemistry–A European …, 2020 - Wiley Online Library
A radical domino cyclisation reaction of N‐cyanamide alkenes, mediated by hydrogen atom
transfer (HAT) has been developed. This method, using PhSiH3 and catalytic Fe (acac) 3 …

Rhodium‐Catalyzed Synthesis of Isoquinolino[1,2‐b]Quinazolines via C−H Annulation in Biomass‐Derived γ‐Valerolactone

L Wang, K Jiang, N Zhang… - Asian Journal of Organic …, 2021 - Wiley Online Library
A rhodium‐catalyzed synthesis of isoquinolino [1, 2‐b] quinazolines via C− H annulation
using vinylene carbonate as an oxidizing acetylene surrogate in biomass‐derived γ …

Synthetic strategies for quinoline based derivatives as potential bioactive heterocycles

S Sharma, K Singh, S Singh - Current Organic Synthesis, 2023 - ingentaconnect.com
Quinoline derivatives are an important class of heterocyclic compounds and possess
various applications in synthetic organic chemistry, medicinal chemistry, material chemistry …