Secondary metabolites from mangrove-associated fungi: Source, chemistry and bioactivities

S Chen, R Cai, Z Liu, H Cui, Z She - Natural product reports, 2022 - pubs.rsc.org
Covering 1989 to 2020 The mangrove forests are a complex ecosystem occurring at tropical
and subtropical intertidal estuarine zones and nourish a diverse group of microorganisms …

Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Identification of unique quinazolone thiazoles as novel structural scaffolds for potential gram-negative bacterial conquerors

J Wang, MF Ansari, CH Zhou - Journal of Medicinal Chemistry, 2021 - ACS Publications
A class of quinazolone thiazoles was identified as new structural scaffolds for potential
antibacterial conquerors to tackle dreadful resistance. Some prepared compounds exhibited …

Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011–2016)

A Hameed, M Al-Rashida, M Uroos, SA Ali… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Quinazoline and quinazolinone scaffolds represent an important class of
biologically active nitrogen heterocyclic compounds. A variety of marketed drugs are based …

Photoinduced homolytic decarboxylative acylation/cyclization of unactivated alkenes with α-keto acid under external oxidant and photocatalyst free conditions: access …

B Sun, R Shi, K Zhang, X Tang, X Shi, J Xu… - Chemical …, 2021 - pubs.rsc.org
A novel and green strategy for the synthesis of acylated quinazolinone derivatives via photo-
induced decarboxylative cascade radical acylation/cyclization of quinazolinone bearing …

FeCl3-Mediated Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Isatins and Trifluoroacetimidoyl Chlorides

LC Wang, S Du, Z Chen, XF Wu - Organic Letters, 2020 - ACS Publications
An FeCl3-mediated cascade coupling/decarbonylative annulation reaction for the efficient
construction of 2-(trifluoromethyl) quinazolin-4 (3 H)-ones has been developed. This …

Synthesis of C6-Substituted Isoquinolino[1,2-b]quinazolines via Rh(III)-Catalyzed C–H Annulation with Sulfoxonium Ylides

J Zhang, X Wang, D Chen, Y Kang, Y Ma… - The Journal of Organic …, 2020 - ACS Publications
We report the synthesis of C6-substituted isoquinolino [1, 2-b] quinazolinones via rhodium
(III)-catalyzed C–H annulation with sulfoxonium ylides and evaluation of the cytotoxic activity …

C–H functionalization of quinazolinones by transition metal catalysis

P Ghosh, B Ganguly, S Das - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Quinazolinone and its congeners are ubiquitous structural motifs found in numerous natural
products due to their wide applications as anticancer, antiviral, anti-inflammatory, antifolate …

Synthesis and Biological Evaluation of Quinazolonethiazoles as New Potential Conquerors towards Pseudomonas Aeruginosa

J Wang, N Battini, MF Ansari… - Chinese Journal of …, 2021 - Wiley Online Library
Main observation and conclusion Novel quinazolonthiazoles were designed and
synthesized as new potential antimicrobial agents by facile multi‐step procedure from o …

[HTML][HTML] Chemical insights into the synthetic chemistry of quinazolines: Recent advances

M Faisal, A Saeed - Frontiers in chemistry, 2021 - frontiersin.org
In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines,
possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV …