Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …

CD9 belongs to the tetraspanin superfamily. Depending on the cell type and associated
molecules, CD9 has a wide variety of biological activities such as cell adhesion, motility …

How the innate and adaptive host immune system miscommunicate to worsen COVID-19
immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune …

Influenza virus strain-specific monoclonal antibodies (mAbs) provide protection independent
of Fc gamma receptor (FcγR) engagement. In contrast, optimal in vivo protection achieved …

Efficient transduction tools are a hallmark for both research and therapy development. Here,
we introduce new insights into the generation of lentiviral vectors with improved …

Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection is a leading
cause of pneumonia and death. The aim of this investigation is to identify the key genes in …

Extracellular vesicles have an important function in cellular communication. Here, we show
that human and mouse monocytes release TGF-β1-transporting vesicles in response to the …

Fasciola hepatica, commonly known as liver fluke, is a trematode that causes Fasciolosis in
ruminants and humans. The outer tegumental coat of F. hepatica (FhTeg) is a complex …

Latency is a major barrier towards virus elimination in HIV-1-infected individuals. Yet, the
mechanisms that contribute to the maintenance of HIV-1 latency are incompletely …

Lentiviral vectors (LVs) have provided an efficient way to integrate our gene of interest into
eukaryote cells. Human immunodeficiency virus (HIV)-derived LVs have been vastly studied …