[HTML][HTML] Revisão sistemática e meta-análise de estudos de diagnóstico e prognóstico: um tutorial

MR Sousa, ALP Ribeiro - Arquivos Brasileiros de Cardiologia, 2009 - SciELO Brasil
As revisões sistemáticas com meta-análise de estudos de exames diagnósticos ou de
fatores prognósticos são ferramentas de pesquisa ainda em fase de desenvolvimento. O …

How useful is thrombocytosis in predicting an underlying cancer in primary care? A systematic review

SER Bailey, OC Ukoumunne, E Shephard… - Family …, 2017 - academic.oup.com
Background. Although the association between raised platelet count (thrombocytosis) and
cancer has been reported in primary and secondary care studies, UK GPs are unaware of it …

[HTML][HTML] The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case–control study using electronic records

S Stapley, TJ Peters, RD Neal, PW Rose… - British journal of …, 2013 - nature.com
Background: Over 15 000 new oesophago-gastric cancers are diagnosed annually in the
United Kingdom, with most being advanced disease. We identified and quantified features of …

Clinical features of primary brain tumours: a case–control study using electronic primary care records

W Hamilton, D Kernick - British Journal of General Practice, 2007 - bjgp.org
Background Around 4500 new primary brain tumours are diagnosed in the UK each year.
Symptoms of these tumours have not previously been studied in primary care. Aim To …

Uncertainty in clinical medicine

B Djulbegovic, I Hozo, S Greenland - Philosophy of medicine, 2011 - Elsevier
Publisher Summary This chapter review and classify uncertainties in clinical medicine.
Epistemic uncertainty is intimately linked to the relationship between theory, evidence, and …

[HTML][HTML] Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain

S Stynes, K Konstantinou, R Ogollah, EM Hay… - PLoS …, 2018 - journals.plos.org
Background Identification of sciatica may assist timely management but can be challenging
in clinical practice. Diagnostic models to identify sciatica have mainly been developed in …

External validation of a COPD diagnostic questionnaire

D Kotz, P Nelemans, CP Van Schayck… - European …, 2008 - Eur Respiratory Soc
The aim of the present study was to determine the external validity of a recently developed
questionnaire for the identification of patients at increased risk of airflow limitation in …

Test research versus diagnostic research

KGM Moons, CJ Biesheuvel, DE Grobbee - Clinical Chemistry, 2004 - academic.oup.com
The diagnostic workup starts with a patient presenting with symptoms or signs suggestive of
a particular disease. The workup is commonly a consecutive process starting with medical …

Applications of prediction models

EW Steyerberg, EW Steyerberg - Clinical prediction models: a practical …, 2019 - Springer
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[HTML][HTML] Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: a large case–control study using electronic records

EA Shephard, RD Neal, P Rose, FM Walter… - British Journal of …, 2015 - bjgp.org
Background Patients with myeloma experience the longest diagnostic delays compared with
patients with other cancers in the UK; 37% are diagnosed through emergency presentations …