Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis

BD Sui, CX Zheng, WM Zhao, K Xuan… - Physiological …, 2023 - journals.physiology.org
The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Single‐cell RNA sequencing in oral science: Current awareness and perspectives

J Wu, Y Ding, J Wang, F Lyu, Q Tang, J Song… - Cell …, 2022 - Wiley Online Library
The emergence of single‐cell RNA sequencing enables simultaneous sequencing of
thousands of cells, making the analysis of cell population heterogeneity more efficient. In …

Determinants of dental pulp stem cell heterogeneity

S Nel, C Durandt, C Murdoch, MS Pepper - Journal of Endodontics, 2022 - Elsevier
Introduction The aim of this review is to provide a narrative review on the determinants of
dental pulp stem cell (DPSC) heterogeneity that may affect the regenerative properties of …

DLP printed hDPSC-loaded GelMA microsphere regenerates dental pulp and repairs spinal cord

Y Qian, J Gong, K Lu, Y Hong, Z Zhu, J Zhang, Y Zou… - Biomaterials, 2023 - Elsevier
Dental pulp regeneration is ideal for irreversible pulp or periapical lesions, and in situ stem
cell therapy is one of the most effective therapies for pulp regeneration. In this study, we …

[HTML][HTML] BDNF/TrkB Is a Crucial Regulator in the Inflammation-Mediated Odontoblastic Differentiation of Dental Pulp Stem Cells

JH Kim, M Irfan, MA Hossain, A George, S Chung - Cells, 2023 - mdpi.com
The odontoblastic differentiation of dental pulp stem cells (DPSCs) associated with caries
injury happens in an inflammatory context. We recently demonstrated that there is a link …

[HTML][HTML] Single-cell atlas of dental pulp stem cells exposed to the oral bacteria Porphyromonas gingivalis and Enterococcus faecalis

W Zhang, T Xu, X Li, Y Zhang, X Zou… - Frontiers in Cell and …, 2023 - frontiersin.org
Porphyromonas gingivalis and Enterococcus faecalis promote the development of pulpitis
and periapical periodontitis. These bacteria are difficult to eliminate from the root canal …

Chronological and Replicative Aging of CD51+/PDGFR-α+ Pulp Stromal Cells

L Yao, F Li, C Yu, H Wang, Y Wang… - Journal of Dental …, 2023 - journals.sagepub.com
As a crucial source of mesenchymal stromal cells, CD51+/PDGFR-α+ human dental pulp
stromal cells (hDPSCs) are promising seeding cells for regenerative medicine. Cellular …

Histological analysis for pulp mineralisation after severe intrusive luxation of immature molars in rats

N Wang, Y Gao, H Ren, L He, Y Zhao - Dental Traumatology, 2023 - Wiley Online Library
Abstract Background/Aim Pulp mineralisation is a survival process that may occur in the pulp
of immature teeth following trauma. However, the mechanism of this process remains …

A review with updated perspectives on in vitro and in vivo wound healing models

MN SARIAN, N ZULKEFLI, S ZAIN… - Turkish Journal of …, 2023 - journals.tubitak.gov.tr
A skin wound or perforation triggers a series of homeostatic reactions to safeguard internal
organs from invasion by pathogens or other substances that could damage body tissues. An …