Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is
a widespread tool for structural analysis across academia and the biopharmaceutical …

Chemistry” on HDX MS. 1 That review covered HDX MS applications from January 2012
through June 2014 and described the publications in terms of sector, geography, and topic …

HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing
antibodies. However, Env structure and organization in its native virion context has eluded …

Nucleosomes, the basic structural units of chromatin, hinder recruitment and activity of
various DNA repair proteins, necessitating modifications that enhance DNA accessibility …

Much of our understanding of protein structure and mechanistic function has been derived
from static high‐resolution structures. As structural biology has continued to evolve it has …

Hydrogen/deuterium exchange mass spectrometry (HDX-MS) has within the last 25 years
evolved to become a well-established technique for analysing the solution-phase …

In light of the COVID‐19 pandemic, there is an ongoing need for diagnostic tools to monitor
the immune status of large patient cohorts and the effectiveness of vaccination campaigns …

Hydrogen deuterium exchange mass spectrometry (HDX-MS) is becoming part of the
standard repertoire of techniques used by molecular biologists to investigate protein …

Hydrogen–deuterium exchange coupled with mass spectrometry (HDX–MS) is widely used
for monoclonal antibody (mAb) epitope mapping, which aids in the development of …

Kinase inhibitors are effective cancer therapies, but resistance often limits clinical efficacy.
Despite the cataloging of numerous resistance mutations, our understanding of kinase …