Nanomaterial-based drug delivery systems for pain treatment and relief: from the delivery of a single drug to co-delivery of multiple therapeutics

Y Xu, X Dong, H Xu, P Jiao, LX Zhao, G Su - Pharmaceutics, 2023 - mdpi.com
The use of nanomaterials in drug delivery systems for pain treatment is becoming
increasingly common. This review aims to summarize how nanomaterial-based drug …

[HTML][HTML] " IUPHAR review-Preclinical Models of Neuropathic Pain: Evaluating Multifunctional Properties of Natural Cannabinoid Receptors Ligands

K Benamar - Pharmacological Research, 2023 - Elsevier
Neuropathic pain remains prevalent and challenging to manage and is often comorbid with
depression and anxiety. The new approach that simultaneously targets neuropathic pain …

Novel drug targets and emerging pharmacotherapies in neuropathic pain

J Bernatoniene, A Sciupokas, DM Kopustinskiene… - Pharmaceutics, 2023 - mdpi.com
Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …

β-Caryophyllene Inhibits Oxaliplatin-Induced Peripheral Neuropathy in Mice: Role of Cannabinoid Type 2 Receptors, Oxidative Stress and Neuroinflammation

JP Agnes, B Dos Santos, RN das Neves, VMM Luciano… - Antioxidants, 2023 - mdpi.com
Peripheral neuropathy is an important adverse effect caused by some chemotherapeutic
agents, including oxaliplatin (OXA). OXA-induced peripheral neuropathy (OIPN) is a …

Synthesis and Physicochemical Stability of a Copaiba Balsam Oil (Copaifera sp.) Nanoemulsion and Prospecting of Toxicological Effects on the Nematode …

IC Bezerra, ERS Santos, JSR Bisneto, PP Perruci… - ACS …, 2024 - ACS Publications
Nanoemulsions are dispersions of oil-in-water (O/W) and water-in-oil (W/O) immiscible
liquids. Thus, our main goal was to formulate a nanoemulsion with low surfactant …

[PDF][PDF] Novel Drug Targets and Emerging Pharmacotherapies in Neuropathic Pain. Pharmaceutics 2023, 15, 1799

J Bernatoniene, A Sciupokas, DM Kopustinskiene… - 2023 - academia.edu
Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …

Electroacupuncture alters cannabinoid receptor 1 and transient receptor potential V1 expression on individual brain regions in a mouse fibromyalgia model

HC Lin, HC Hsu, YW Lin - 2024 - researchsquare.com
Fibromyalgia, one of the most challenging pains to treat, lacks impartial considerations for
diagnosis and useful assessment. The core symptoms are persistent extensive pain …

Elucidating the Therapeutic Effects of Individual Compounds Found in Cannabis Sativa for Pain Management and Reward Liability

AM Schwarz - 2024 - repository.arizona.edu
The Cannabis plant contains over 550 different chemicals, many of which are bioactive and
understudied. Despite the complexity of Cannabis pharmacology, most work has …

Relação do uso do canabidiol na dor: uma revisão sistemática

ME Comunello, MP Rangel - Research, Society and Development, 2023 - rsdjournal.org
Introduction: Pain can be incapacitating depending on its intensity and duration, causing the
individual to have a loss in quality of life. Currently, the recommended treatments present …

Marketing promocional en la difusión del aceite medicinal cáñamo en la ciudad de Guayaquil 2022–2023

FJ Heredia Marín - 2023 - repositorio.ulvr.edu.ec
En la población ecuatoriana se presentan una serie de afecciones inflamatorias, por
ejemplo, diferentes tipos de cáncer, fracturas de huesos largos, mal de Parkinson. Para su …