[HTML][HTML] Pharmacogenetics of type 2 diabetes—progress and prospects
YA Nasykhova, ZN Tonyan, AA Mikhailova… - International Journal of …, 2020 - mdpi.com
Type 2 diabetes mellitus (T2D) is a chronic metabolic disease resulting from insulin
resistance and progressively reduced insulin secretion, which leads to impaired glucose …
resistance and progressively reduced insulin secretion, which leads to impaired glucose …
The gut microbial endocrine organ in type 2 diabetes
W Massey, JM Brown - Endocrinology, 2021 - academic.oup.com
Historically, the focus of type II diabetes mellitus (T2DM) research has been on host
metabolism and hormone action. However, emerging evidence suggests that the gut …
metabolism and hormone action. However, emerging evidence suggests that the gut …
Microbial-driven genetic variation in holobionts
I Zilber-Rosenberg, E Rosenberg - FEMS Microbiology Reviews, 2021 - academic.oup.com
Genetic variation in holobionts (host and microbiome), occurring in both host and
microbiome genomes, can be observed from two perspectives: observable variations and …
microbiome genomes, can be observed from two perspectives: observable variations and …
[HTML][HTML] Long-term treatment of polysaccharides-based hydrogel microparticles as oral insulin delivery in streptozotocin-induced type 2 diabetic mice
Y Yang, S Chen, Y Liu, Y Huang, KL Cheong… - Biomedicine & …, 2021 - Elsevier
To develop a more effective and safer drug for the treatment of type 2 diabetes mellitus
(T2DM), polysaccharides-based hydrogel microparticles as oral insulin delivery was …
(T2DM), polysaccharides-based hydrogel microparticles as oral insulin delivery was …
Evolution of Bioinformatics and its impact on modern bio-science in the twenty-first century: Special attention to pharmacology, plant science and drug discovery
Bioinformatics is inherently an innovative field that is situated at the limit of life and computer
sciences that allowed new technological advances in genome sequencing, data processing …
sciences that allowed new technological advances in genome sequencing, data processing …
[HTML][HTML] Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets
Abstract Type 2 diabetes (T2D) is the fastest growing non-infectious disease worldwide.
Impaired insulin secretion from pancreatic beta-cells is a hallmark of T2D, but the …
Impaired insulin secretion from pancreatic beta-cells is a hallmark of T2D, but the …
[HTML][HTML] Genetic perspectives on childhood monogenic diabetes: Diagnosis, management, and future directions
HY Sun, XY Lin - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
Monogenic diabetes is caused by one or even more genetic variations, which may be
uncommon yet have a significant influence and cause diabetes at an early age. Monogenic …
uncommon yet have a significant influence and cause diabetes at an early age. Monogenic …
[HTML][HTML] Recent progress in the diagnosis and management of type 2 diabetes mellitus in the era of COVID-19 and single cell multi-omics technologies
K Kupai, T Várkonyi, S Török, V Gáti, Z Czimmerer… - Life, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is one of the world's leading causes of death and life-
threatening conditions. Therefore, we review the complex vicious circle of causes …
threatening conditions. Therefore, we review the complex vicious circle of causes …
[HTML][HTML] Diabetes: discovery of insulin, genetic, epigenetic and viral infection mediated regulation
S Ghosh, S Mahalanobish, PC Sil - The Nucleus, 2021 - Springer
Diabetes mellitus, commonly referred to as diabetes, is a combination of many metabolic
diseases. Insulin deficiency in our body is the main cause of diabetes. Insulin is one of the …
diseases. Insulin deficiency in our body is the main cause of diabetes. Insulin is one of the …
[HTML][HTML] A 646C> G (rs41423247) polymorphism of the glucocorticoid receptor as a risk factor for hyperglycaemia diagnosed in pregnancy—data from an …
A Zawiejska, A Bogacz, R Iciek, A Lewicka-Rabska… - Acta Diabetologica, 2021 - Springer
Aim Hyperglycaemia diagnosed in pregnancy (HiP) is a serious and frequent complication
of pregnancy, increasing the risk for adverse maternal and neonatal outcomes. Investigate …
of pregnancy, increasing the risk for adverse maternal and neonatal outcomes. Investigate …