This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Acid-base balance is critical for normal life. Acute and chronic disturbances impact cellular
energy metabolism, endocrine signaling, ion channel activity, neuronal activity, and …

Morphogenesis, homeostasis, and regeneration of epithelial tissues rely on the accurate
orientation of cell divisions, which is specified by the mitotic spindle axis. To remain in the …

Aldosterone is classically associated with the regulation of salt and potassium homeostasis
but has also profound effects on acid-base balance. During acidosis, circulating aldosterone …

Glycosphingolipids (GSLs) are a group of plasma-membrane lipids notable for their
extremely diverse glycan head groups. The metabolic pathways for GSLs, including the …

Ammonia metabolism has a critical role in acid-base homeostasis and in other cellular
functions. Kidneys have a central role in bicarbonate generation, which occurs through the …

Simple Summary Renal cell carcinoma (RCC) is among the most common cancer types in
both men and women, and its early detection significantly improves survival. Minimally …

Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-
galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in …

Matrix-assisted laser desorption/ionization coupled with Orbitrap mass spectrometry (MALDI-
Orbitrap-MS) is used for the clinical study of patients with renal cell carcinoma (RCC), as the …

Renal tubular acidosis (RTA) represents a group of diseases characterized by (1) a normal
anion gap metabolic acidosis;(2) abnormalities in renal HCO 3− absorption or new renal …