The obesity pandemic continues unabated despite a persistent public health campaign to
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …

Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …

Thousands of natural or manufactured chemicals were defined as endocrine-disrupting
chemicals (EDCs) because they can interfere with hormone activity and the endocrine …

The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

Plastics are complex chemical mixtures of polymers and various intentionally and
nonintentionally added substances. Despite the well-established links between certain …

Food contact materials (FCMs) and food contact articles are ubiquitous in today's globalized
food system. Chemicals migrate from FCMs into foodstuffs, so called food contact chemicals …

More people now have obesity than suffer from starvation thanks to our modern food system.
Agriculture was transformed over the 20th century by a variety of technological …

Background An increasing number of studies have reported that prenatal per-and
polyfluoroalkyl substances (PFAS) exposure may increase childhood adiposity. However …

Subclinical inflammation is linked to comorbidities and risk factors, consolidating the
diagnosis of chronic non-communicable diseases, such as insulin resistance …

Di-tert-butylphenol (2, 4-DTBP) is an important commercial antioxidant and a toxic natural
secondary metabolite that has been detected in humans. However, there is scant …