Blast injuries

SJ Wolf, VS Bebarta, CJ Bonnett, PT Pons, SV Cantrill - The Lancet, 2009 - thelancet.com
Health-care providers are increasingly faced with the possibility of needing to care for
people injured in explosions, but can often, however, feel undertrained for the unique …

Precision medicine and heterogeneity of treatment effect in therapies for ARDS

YA Khan, E Fan, ND Ferguson - Chest, 2021 - Elsevier
ARDS is a clinically heterogeneous syndrome, rather than a distinct disease. This
heterogeneity at least partially explains the difficulty in studying treatments for these patients …

Impact of ventilator adjustment and sedation–analgesia practices on severe asynchrony in patients ventilated in assist-control mode

G Chanques, JP Kress, A Pohlman, S Patel… - Critical care …, 2013 - journals.lww.com
Objectives: Breath-stacking asynchrony during assist-control-mode ventilation may be
associated with increased tidal volume and alveolar pressure that could contribute to …

Physiologic response to varying levels of pressure support and neurally adjusted ventilatory assist in patients with acute respiratory failure

D Colombo, G Cammarota, V Bergamaschi… - Intensive care …, 2008 - Springer
Objective Neurally adjusted ventilatory assist (NAVA) is a new mode wherein the assistance
is provided in proportion to diaphragm electrical activity (EAdi). We assessed the physiologic …

Spontaneous breathing improves lung aeration in oleic acid–induced lung injury

H Wrigge, J Zinserling, P Neumann… - The Journal of the …, 2003 - pubs.asahq.org
Background Experimental and clinical studies have shown reduction in intrapulmonary
shunt with improved oxygenation by spontaneous breathing with airway pressure release …

Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support

N Xirouchaki, E Kondili, K Vaporidi, G Xirouchakis… - Intensive care …, 2008 - Springer
Objectives It is not known if proportional assist ventilation with load-adjustable gain factors
(PAV+) may be used as a mode of support in critically ill patients. The aim of this study was …

Topographic distribution of tidal ventilation in acute respiratory distress syndrome: effects of positive end-expiratory pressure and pressure support

T Mauri, G Bellani, A Confalonieri… - Critical care …, 2013 - journals.lww.com
Objective: Acute respiratory distress syndrome is characterized by collapse of gravitationally
dependent lung regions that usually diverts tidal ventilation toward nondependent regions …

Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial

A Demoule, M Clavel, C Rolland-Debord, S Perbet… - Intensive care …, 2016 - Springer
Purpose Neurally adjusted ventilatory assist (NAVA) is a ventilatory mode that tailors the
level of assistance delivered by the ventilator to the electromyographic activity of the …

Sigh improves gas exchange and lung volume in patients with acute respiratory distress syndrome undergoing pressure support ventilation

N Patroniti, G Foti, B Cortinovis, E Maggioni… - The Journal of the …, 2002 - pubs.asahq.org
Background The aim of our study was to assess the effect of periodic hyperinflations (sighs)
during pressure support ventilation (PSV) on lung volume, gas exchange, and respiratory …

Patient–ventilator interaction in ARDS patients with extremely low compliance undergoing ECMO: a novel approach based on diaphragm electrical activity

T Mauri, G Bellani, G Grasselli, A Confalonieri… - Intensive care …, 2013 - Springer
Purpose Patients with acute respiratory distress syndrome (ARDS) requiring extracorporeal
membrane oxygenation (ECMO) usually present very low respiratory system compliance …