New halogen-containing drugs approved by FDA in 2021: An overview on their syntheses and pharmaceutical use
This review describes the recent Food and Drug Administration (FDA)-approved drugs (in
the year 2021) containing at least one halogen atom (covalently bound). The structures …
the year 2021) containing at least one halogen atom (covalently bound). The structures …
Marine bacterial secondary metabolites: A treasure house for structurally unique and effective antimicrobial compounds
The prevalence of antimicrobial resistance reduces the effectiveness of antimicrobial drugs
in preventing and treating infectious diseases caused by pathogenic organisms, such as …
in preventing and treating infectious diseases caused by pathogenic organisms, such as …
Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors
Since its first report in December 2019, the novel coronavirus virus, SARS-CoV-2, has
caused an unprecedented global health crisis and economic loss imposing a tremendous …
caused an unprecedented global health crisis and economic loss imposing a tremendous …
Marine drugs: Biology, pipelines, current and future prospects for production
The marine environment is a huge reservoir of biodiversity and represents an excellent
source of chemical compounds, some of which have large economical values. In the urgent …
source of chemical compounds, some of which have large economical values. In the urgent …
A propitious role of marine sourced polysaccharides: Drug delivery and biomedical applications
Numerous compounds, with extensive applications in biomedical and biotechnological
fields, are present in the oceans, which serve as a prime renewable source of natural …
fields, are present in the oceans, which serve as a prime renewable source of natural …
The application of plant growth-promoting rhizobacteria in Solanum lycopersicum production in the agricultural system: a review
Food safety is a significant challenge worldwide, from plantation to cultivation, especially for
perishable products such as tomatoes. New eco-friendly strategies are needed, and …
perishable products such as tomatoes. New eco-friendly strategies are needed, and …
Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis
K Li, S Chen, X Pang, J Cai, X Zhang, Y Liu… - European Journal of …, 2022 - Elsevier
The mangrove forests are a complex ecosystem, and the microbial communities in
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …
An overview on the nutritional and bioactive components of green seaweeds
J Xu, W Liao, Y Liu, Y Guo, S Jiang, C Zhao - Food Production, Processing …, 2023 - Springer
Green seaweed, as the most abundant species of macroseaweeds, is an important marine
biological resource. It is a rich source of several amino acids, fatty acids, and dietary fibers …
biological resource. It is a rich source of several amino acids, fatty acids, and dietary fibers …
Metabolites with antioxidant activity from marine macroalgae
Reactive oxygen species (ROS) attack biological molecules, such as lipids, proteins,
enzymes, DNA, and RNA, causing cellular and tissue damage. Hence, the disturbance of …
enzymes, DNA, and RNA, causing cellular and tissue damage. Hence, the disturbance of …
Structure-based pharmacophore modeling, virtual screening, molecular docking, ADMET, and molecular dynamics (MD) simulation of potential inhibitors of PD-L1 …
L Luo, A Zhong, Q Wang, T Zheng - Marine Drugs, 2021 - mdpi.com
Background: In the past decade, several antibodies directed against the PD-1/PD-L1
interaction have been approved. However, therapeutic antibodies also exhibit some …
interaction have been approved. However, therapeutic antibodies also exhibit some …