Antioxidant, anti-inflammatory, anti-menopausal, and anti-cancer effects of lignans and their metabolites

WY Jang, MY Kim, JY Cho - International journal of molecular sciences, 2022 - mdpi.com
Since chronic inflammation can be seen in severe, long-lasting diseases such as cancer,
there is a high demand for effective methods to modulate inflammatory responses. Among …

Lignans from linseed (Linum usitatissimum L.) and its allied species: Retrospect, introspect and prospect

H Chhillar, P Chopra, MA Ashfaq - Critical Reviews in Food …, 2021 - Taylor & Francis
Lignans are complex diphenolic compounds representing phytoestrogens and occur widely
across the plant kingdom. Formed by the coupling of two coniferyl alcohol residues, lignans …

Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling

X Xie, X Chang, L Chen, K Huang, J Huang… - Molecular and Cellular …, 2013 - Elsevier
The accumulation of glomerular extracellular matrix proteins, especially fibronectin (FN), is a
critical pathological characteristic of diabetic renal fibrosis. Inflammation mediated by …

Flaxseed lignans and polyphenols enhanced activity in streptozotocin-induced diabetic rats

D Draganescu, C Andritoiu, D Hritcu, G Dodi, MI Popa - Biology, 2021 - mdpi.com
Simple Summary Diabetes mellitus is a metabolic condition that affects millions of people
globally. The present study highlights the enhanced activity of flaxseed lignans and …

Plant polyphenols mechanisms of action on insulin resistance and against the loss of pancreatic beta cells

C Papuc, GV Goran, CN Predescu… - Critical reviews in …, 2021 - Taylor & Francis
Diabetes mellitus describes a group of metabolic disorders characterized by a prolonged
period hyperglycemia with long-lasting detrimental effects on the cardiovascular and …

Distribution, biosynthesis and therapeutic potential of lignans

NS Plaha, S Awasthi, A Sharma, N Kaushik - 3 Biotech, 2022 - Springer
Lignans have long been known for their abundant therapeutic properties due to their
polyphenolic structure. Linseed is the richest plant source of lignans and has been studied …

Hypoglycemic and hypolipidemic effects of oxymatrine in high-fat diet and streptozotocin-induced diabetic rats

C Guo, C Zhang, L Li, Z Wang, W Xiao, Z Yang - Phytomedicine, 2014 - Elsevier
Oxymatrine, a quinolizidine alkaloid, has been widely used for the treatment of hepatitis. In
this study, we investigated the hypoglycemic and hypolipidemic effects and new …

[HTML][HTML] Antidiabetic activity of Sargassum hystrix extracts in streptozotocin-induced diabetic rats

TL Gotama, A Husni - Preventive Nutrition and Food Science, 2018 - ncbi.nlm.nih.gov
The objective of this research was to determine the potential effects of Sargassum hystrix
extracts (SHE) on the glucose levels, lipid profile, and pancreas of streptozotocin (STZ) …

Neuromodulatory effects of hesperidin in mitigating oxidative stress in streptozotocin induced diabetes

M Ashafaq, L Varshney, MHA Khan… - BioMed research …, 2014 - Wiley Online Library
Oxidative stress has been implicated in pathogenesis of streptozotocin‐(STZ‐) induced
diabetes mellitus and its complication in central nervous system (CNS). Recent studies have …

Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats

M Eltimamy, M Elshamarka, M Aboelsaad… - Journal of Diabetes & …, 2022 - Springer
Background A considerable amount of attention has been recently paid to the discovery of
effective natural antidiabetic drugs. Terminalia chebula is considered as the mother of herbs …