Andrographolide and Deoxyandrographolide Inhibit Protease and IFN-Antagonist Activities of Foot-and-Mouth Disease Virus 3Cpro

S Theerawatanasirikul, V Lueangaramkul… - Animals, 2022 - mdpi.com
Simple Summary Foot-and-Mouth disease (FMD) is a re-emerging infectious disease that
poses a negative impact on livestock production and economics worldwide. It is also …

Effects of the natural flavonoid quercetin on arenavirus Junín infection

AE Alvarez De Lauro, MA Pelaez, AB Marquez… - Viruses, 2023 - mdpi.com
There is no specific chemotherapy approved for the treatment of pathogenic arenaviruses
that cause severe hemorrhagic fever (HF) in the population of endemic regions in America …

[HTML][HTML] Secondary metabolites: Alkaloids and flavonoids in medicinal plants

H Zandavar, MA Babazad - Herbs and Spices-New Advances, 2023 - intechopen.com
Secondary metabolites (SMs) are natural compounds produced mainly by bacteria, fungi,
and plants. They are low molecular weight compounds that have a wide range of chemical …

Identifying the natural compound Catechin from tropical mangrove plants as a potential lead candidate against 3CLpro from SARS-CoV-2: An integrated in silico …

RK Jha, RJ Khan, A Parthiban, E Singh… - Journal of …, 2022 - Taylor & Francis
Abstract SARS-CoV-2, a member of beta coronaviruses, is a single-stranded, positive-sense
RNA virus responsible for the COVID-19 pandemic. With global fatalities of the pandemic …

Identification of flavonoids of Kalanchoe Pinnata as candidate drugs for COVID-19 gamma-variant treatment

Y Aurora, IPN Tarigan, NMM Suryanto… - Malaysian Journal of …, 2022 - mjfas.utm.my
Abstract Treatment of COVID-19 that is based on plants could be a more cost-effective
therapy against the disease. Flavonoids, a group of compounds that have been observed to …

Alkyne-tagged apigenin, a chemical tool to navigate potential targets of flavonoid anti-dengue leads

K Hengphasatporn, B Kaewmalai, S Jansongsaeng… - Molecules, 2021 - mdpi.com
A flavonoid is a versatile core structure with various cellular, immunological, and
pharmacological effects. Recently, flavones have shown anti-dengue activities by interfering …

Flavonoids of Zinnia elegans: Chemical profile and in vitro antioxidant and in silico anti-COVID-19 activities

MN Samy, AAR Gomaa, EZ Attia, MAA Ibrahim… - South African Journal of …, 2022 - Elsevier
Chemical profiles of total alcohol extract and various derived fractions of aerial parts of
Zinnia elegans were studied. Accordingly, eight flavonoids were isolated from the ethyl …

The inhibitory effects of Juglanin on adipogenesis in 3T3-L1 adipocytes

G Wang, B Wu, W Xu, X Jin, K Wang… - Drug Design …, 2020 - Taylor & Francis
Introduction Deregulation of adipogenesis plays an important role in obesity and other
metabolism disorders. PPAR, C/EBP and SREBP1c are key transcriptional factors involved …

Analysis of galangin and its in vitro/in vivo metabolites via ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

F Zhao, Y Ma, J Yin, Y Li, Y Cao, L Zhang - Metabolites, 2022 - mdpi.com
Galangin, a naturally available flavonoid, induces a variety of pharmacological activities and
biological effects via several mechanisms. However, in vivo metabolism of galangin has not …

The potential of Ethiopian medicinal plants to treat emergent viral diseases

M Fekadu, E Lulekal, S Tesfaye, M Ruelle… - Phytotherapy …, 2023 - Wiley Online Library
Ethiopians have deep‐rooted traditions of using plants to treat ailments affecting humans
and domesticated animals. Approximately 80% of the population continues to rely on …