Spinal cord injury (SCI) is the most common disabling spinal injury, and the complex
pathological process can eventually lead to severe neurological dysfunction. Many studies …

Spinal cord injury (SCI) is a serious central nervous system disease, and secondary injury,
including oxidative stress, the inflammatory response and accompanying neuronal …

Spinal cord injury (SCI) represents a devastating injury to the central nervous system (CNS)
that is responsible for impaired mobility and sensory function in SCI patients. The hallmarks …

Neurodegenerative disorders represent a major and growing healthcare challenge globally.
Among the numerous molecular pathways implicated in their pathogenesis, calpain …

Tetramethylpyrazine (TMP) has been effectively used for treating spinal cord injury (SCI) due
to its anti-inflammatory, antioxidant, and neuroprotective activity. However, its clinical …

Spinal cord injury (SCI) is catastrophic to humans and society. However, there is currently no
effective treatment for SCI. Autophagy is known to serve critical roles in both the …

Cerium oxide nanoparticles (CNPs) are biocompatible nanozymes exerting multifunctional
biomimetic activities, including superoxide dismutase (SOD), catalase, glutathione …

Reactive astrocytes are implicated in traumatic spinal cord injury (TSCI). Interestingly, naïve
astrocytes can easily transform into neurotoxic reactive astrocytes (A1s) with inflammatory …

The combination of composite nerve materials prepared using degradable polymer
materials with biological or physical factors has received extensive attention as a means to …

Spinal cord injury (SCI) often causes loss of sensory and motor function resulting in a
significant reduction in quality of life for patients. Currently, no therapies are available that …