Mechanical forces play a vital role in biological processes at molecular and cellular levels,
significantly impacting various diseases such as cancer, cardiovascular disease, and COVID …

Activation of integrins is crucial for recruitment of flowing leukocytes to inflammatory or
injured vascular sites, but their spatiotemporal characteristics are incompletely understood …

Naive T lymphocytes traffic through the organism in search for antigen, alternating between
blood and secondary lymphoid organs. Lymphocyte homing to lymph nodes relies on …

Small, single-layer microfluidic paper-based analytical devices (µPADs) offer potential for a
range of point-of-care applications; however, they have been limited to low flow rates. Here …

Abstract Background and Aims The anti-MAdCAM-1 antibody ontamalimab demonstrated
efficacy in a phase II trial in ulcerative colitis and results of early terminated phase III trials …

Naïve T lymphocytes traffic through the organism in their search for antigen, alternating
between blood and secondary lymphoid organs. Lymphocyte homing to lymph nodes relies …

Аннотация Формирование внеклеточных ДНК-ловушек нейтрофилов (NET-оз)–
механизм запрограммированной клеточной смерти лейкоцитов, имеющий исходно …

Cardiovascular disease accounts for one third of deaths worldwide, of which over 75% are
in low-and middle-income countries. Platelets and von Willebrand Factor play a central role …

Naive T lymphocytes traffic through the organism in search for antigen, alternating between
blood and secondary lymphoid organs. Lymphocyte homing to lymph nodes relies on …

Ontamalimab is a therapeutic candidate antibody targeting MAdCAM-1, intended for the
treatment of inflammatory bowel diseases (IBD), of which the main entities are ulcerative …