[HTML][HTML] Impact of genetic and environmental factors on autoimmune hepatitis

K Zachou, P Arvaniti, A Lyberopoulou… - Journal of Translational …, 2021 - Elsevier
Autoimmune hepatitis (AIH) is a chronic non-resolving liver disease characterized by diffuse
hypergammaglobulinemia, the presence of autoantibodies and characteristic histological …

Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response

T Higuchi, S Oka, H Furukawa, S Tohma… - Human Genomics, 2021 - Springer
Autoimmune hepatitis (AIH) is a rare chronic progressive liver disease with autoimmune
features. It mainly affects middle-aged women. AIH is occasionally complicated with liver …

Genome‐wide meta‐analysis identifies susceptibility loci for autoimmune hepatitis type 1

Y Li, Y Sun, Y Liu, B Wang, J Li, H Wang, H Zhang… - …, 2022 - Wiley Online Library
Abstract Background and Aims Autoimmune hepatitis (AIH) is a rare and chronic
autoimmune liver disease. While genetic factors are believed to play a crucial role in the …

[HTML][HTML] Discovery of Genomic Loci for Liver Health and Steatosis Reveals Overlap with Glutathione Redox Genetics

RL Koch, JB Stanton, S McClatchy, GA Churchill… - Redox Biology, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition in the
United States, encompassing a wide spectrum of liver pathologies including steatosis …

Role of deleterious single nucleotide variants in the coding regions of TNFAIP3 for Japanese autoimmune hepatitis with cirrhosis

T Higuchi, S Oka, H Furukawa, M Nakamura… - Scientific Reports, 2019 - nature.com
Autoimmune hepatitis (AIH) is an autoimmune liver disease and cirrhosis is sometimes
complicated with AIH at diagnosis, influencing its prognosis. TNFAIP3 gene encodes A20 …

自身免疫性肝炎发病机制的研究现状.

曹亦楠, 周桂琴, 王宪波, 李斌… - Journal of Clinical …, 2019 - search.ebscohost.com
曹亦楠1,2 ,周桂琴1 ,王宪波1 ,李斌1 ,冯颖1 ,胡超群 Page 1 自身免疫性肝炎发病机制的研究现状
曹亦楠1,2 ,周桂琴1 ,王宪波1 ,李斌1 ,冯颖1 ,胡超群2 (1 首都医科大学附属北京地坛医院中西医 …

[HTML][HTML] Associations between HLA class II alleles and IgE sensitization to allergens in the Qatar Biobank cohort

T Khan, IM Ledoux, F Aziz, F Al Ali, E Chin-Smith… - Journal of Allergy and …, 2023 - Elsevier
Background Allergic disorders are the consequence of IgE sensitization to allergens.
Population studies have shown that certain human leukocyte antigen (HLA) alleles are …

TNFAIP3, TNIP1, and MyD88 Polymorphisms Predict Septic-Shock-Related Death in Patients Who Underwent Major Surgery

MÁ Jiménez-Sousa, A Fadrique, P Liu… - Journal of Clinical …, 2019 - mdpi.com
Background: In many immune-related diseases, inflammatory responses and several clinical
outcomes are related to increased NF-κB activity. We aimed to evaluate whether SNPs …

不同抗体状态的自身免疫性肝炎肝脏组织病理学与临床特征的比较.

高媛娇, 林妍洁, 杨柳, 毕潇月, 邓雯… - Journal of Clinical …, 2022 - search.ebscohost.com
高媛娇1 ,林妍洁2 ,杨柳1 ,毕潇月1 ,邓雯1 ,蒋婷婷1 ,孙芳芳1 ,路遥1 , 张璐1 ,李明1 Page 1 !89:;341!
不同抗体状态的自身免疫性肝炎肝脏组织病理学 与临床特征的比较 高媛娇1 ,林妍洁2 ,杨柳1 ,毕潇月 …

Research advances in the pathogenesis of autoimmune hepatitis

C YiNan, Z GuiQin, W XianBo, L Bin, H ChaoQun - 临床肝胆病杂志, 2019 - lcgdbzz.org
Autoimmune hepatitis (AIH) is a progressive chronic inflammatory liver disease with
unknown etiology. At present, genetic susceptibility and environmental factors are …