Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of
nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and …

For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Objective To identify research priorities in the management, epidemiology, outcome and
underlying causes of sepsis and septic shock. Design A consensus committee of 16 …

Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

Background: Administering antimicrobial agents before obtaining blood cultures could
potentially decrease time to treatment and improve outcomes, but it is unclear how this …

The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Combination antibiotic therapy for invasive infections with Gram-negative bacteria is
employed in many health care facilities, especially for certain subgroups of patients …