[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - Food and Chemical …, 2017 - Elsevier
The unique properties of nanomaterials (NMs) are beneficial in numerous industrial and
medical applications. However, they could also induce unintended effects. Thus, a proper …

In pursuit of the first recognized epigenetic signal––DNA methylation: A 1976 to 2008 synopsis

W Doerfler - Epigenetics, 2008 - Taylor & Francis
A synopsis will be presented of work on DNA methylation, the first epigenetic signal to be
recognized. In the author´ s laboratory, the following problems dealing with DNA methylation …

[HTML][HTML] Identification of a unique epigenetic profile in women with diminished ovarian reserve

KW Olsen, J Castillo-Fernandez, AC Chan… - Fertility and …, 2021 - Elsevier
Objective To investigate whether epigenetic profiles of mural granulosa cells (MGC) and
leukocytes from women with diminished ovarian reserve (DOR) differ from those of women …

A mathematical study of the influence of hypoxia and acidity on the evolutionary dynamics of cancer

G Fiandaca, M Delitala, T Lorenzi - Bulletin of Mathematical Biology, 2021 - Springer
Hypoxia and acidity act as environmental stressors promoting selection for cancer cells with
a more aggressive phenotype. As a result, a deeper theoretical understanding of the spatio …

Modeling the emergence of phenotypic heterogeneity in vascularized tumors

C Villa, MA Chaplain, T Lorenzi - SIAM Journal on Applied Mathematics, 2021 - SIAM
We present a mathematical study of the emergence of phenotypic heterogeneity in
vascularized tumors. Our study is based on formal asymptotic analysis and numerical …

Invasion fronts and adaptive dynamics in a model for the growth of cell populations with heterogeneous mobility

T Lorenzi, B Perthame, X Ruan - European Journal of Applied …, 2022 - cambridge.org
We consider a model for the dynamics of growing cell populations with heterogeneous
mobility and proliferation rate. The cell phenotypic state is described by a continuous …

[PDF][PDF] Реабилитация женщин после неразвивающейся беременности

ЛР Агабабян, МБ кизи Хамрокулова - Science and Education, 2023 - openscience.uz
Реабилитация женщин после неразвивающейся беременности Rehabilitation of women
Page 1 Реабилитация женщин после неразвивающейся беременности Лариса …

Hypoxia-resistance heterogeneity in tumours: the impact of geometrical characterization of environmental niches and evolutionary trade-offs. A mathematical …

G Chiari, G Fiandaca, ME Delitala - Mathematical Modelling of …, 2023 - mmnp-journal.org
In the study of cancer evolution and therapeutic strategies, scientific evidence shows that a
key dynamics lies in the tumour-environment interaction. In particular, oxygen concentration …

Hypoxia-related radiotherapy resistance in tumors: treatment efficacy investigation in an eco-evolutionary perspective

G Chiari, G Fiandaca, ME Delitala - Frontiers in Applied Mathematics …, 2023 - frontiersin.org
Introduction In the study of therapeutic strategies for the treatment of cancer, eco-
evolutionary dynamics are of particular interest, since characteristics of the tumor population …

Discrete and continuum models for the coevolutionary dynamics between CD8+ cytotoxic T lymphocytes and tumour cells

L Almeida, C Audebert, E Leschiera… - … Medicine and Biology …, 2023 - academic.oup.com
We present an individual-based model for the coevolutionary dynamics between CD8+
cytotoxic T lymphocytes (CTLs) and tumour cells. In this model, every cell is viewed as an …