Simple Summary Nuclear protein 1 (NUPR1) is activated in cellular stress and is expressed
at high levels in cancer cells. Much evidence has been gathered supporting its critical role in …

The epithelial–mesenchymal transition (EMT) plays a crucial role in pancreatic ductal
adenocarcinoma (PDAC) development and progression. TWIST activated by intra-tumoral …

Abstract Nuclear protein‑1 (NUPR1) is also known as Com‑1 or p8. It is a protein primarily
found in the nucleus of various cells, including cancer cells, and it has been found to play an …

Opportunities to interrogate the immune responses in the injured tissue of living patients
suffering from acute sterile injuries such as stroke and heart attack are limited. We leveraged …

Polyphenols are a family of naturally occurring organic compounds, majorly present in fruits,
vegetables, and cereals, characterised by multiple phenol units, including flavonoids, tannic …

Abstract Aurora kinase A (Aurora-A), a serine/threonine kinase, plays a pivotal role in
various cellular processes, including mitotic entry, centrosome maturation and spindle …

Background Radiotherapy (RT) is one of the major therapeutic approaches to hepatocellular
carcinoma (HCC). Ionizing radiation (IR) inducing the generation of reactive oxygen species …

Over the past few decades, research on reactive oxygen species (ROS) has revealed their
critical role in the initiation and progression of cancer by virtue of various transcription …

O-GlcNAcylation is important in the development and progression of pancreatic ductal
adenocarcinoma (PDAC). The glycosyltransferase EGF domain-specific O-linked GlcNAc …

High fat feeding impairs skeletal muscle metabolic flexibility and induces insulin resistance,
whereas exercise training exerts positive effects on substrate handling and improves insulin …