It was already described that genetic inhibition of NUPR1 induces tumor growth arrest. In
this paper we studied the metabolism changes after NUPR1 downregulation in pancreatic …

To support cellular homeostasis and mitigate chemotherapeutic stress, cancer cells must
gain a series of adaptive intracellular processes. Here we identify that NUPR1, a tamoxifen …

The mammalian CNS is capable of tolerating chronic hypoxia, but cell type-specific
responses to this stress have not been systematically characterized. In the Norrin KO (Ndp …

Human endogenous retroviruses (HERVs) are suggested to be involved in the development
of certain diseases, especially cancers. To elucidate the function of HERV-K Env protein in …

Pancreatic cancer is one of the deadliest cancers in the world, causing hundreds of
thousands of deaths worldwide annually. Because of late diagnosis, rapid metastasis and …

Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancer types where the 5-year
survival rate shows no improvement. Despite conflicting evidence, the majority of data points …

Cadmium (Cd), an established carcinogen, is a risk factor for oral squamous cell carcinoma
(OSCC). Macroautophagy/autophagy is proposed to play a pivotal role in Cd-mediated …

The anti-proliferative potential of Passiflora mollissima seeds, an underexplored agri-food
waste, was investigated in this work by evaluating the molecular changes induced at …

Recurrence and metastasis affect the survival rate of breast cancer patients. The
fundamental reason lies in the lack of understanding of the mechanism of breast cancer …

This study was performed to investigate the effects of dietary inclusion of 20% rapeseed
meal (RSM) as an alternative to soybean meal (SBM) in a three-month feeding experiment …