Chemoresistance can be increased by cells in the polyaneuploid cancer cells (PACC) state,
a major cause of treatment failure in various cancers. The life cycle of cells in the PACC state …

NUPR1 is a transcription factor that has attracted great attention because of its various roles
in cancer. Several studies were carried out to determine its molecular targets and …

Background. The Nuclear protein 1 gene was first discovered in acute pancreatitis and
functions as an oncogene in cancer progression and drug resistance. However, the role of …

目的探讨Aurora-A 的表达与胰腺癌吉西他滨耐药之间的关系. 方法40 只裸鼠采用随机数字表法
分为两组, 分别采用人胰腺癌细胞株PANC-1 和吉西他滨耐药株PANC-1/R2 …

Introduction (which was not certified by peer review) is the author/funder. All rights reserved.
No reuse allowed without permission. The copyright holder for this preprint this version …

El descubrimiento de fármacos es un proceso complejo que se centra en el desarrollo de
nuevos compuestos que puedan utilizarse para tratar y aliviar enfermedades que …

Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms that originate
from neuroendocrine stem cells and express both neural and endocrine markers. They are …

Worldwide, there were an estimated 1.8 million new cases of colorectal cancer (CRC) and
0.9 million deaths by its cause in 2018 [1], consequently alternative strategies and new anti …

Background: NUPR1 was described as a transcriptional factor involved in the regulation of
various cellular stress-response genes, playing a crucial role in the condition of the …