Macrophage M1/M2 polarization

C Yunna, H Mengru, W Lei, C Weidong - European journal of …, 2020 - Elsevier
Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Sex hormone signaling and regulation of immune function

JP Hoffmann, JA Liu, K Seddu, SL Klein - Immunity, 2023 - cell.com
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …

Macrophage efferocytosis in health and disease

S Razi, J Yaghmoorian Khojini… - Cell biochemistry …, 2023 - Wiley Online Library
Creating cellular homeostasis within a defined tissue typically relates to the processes of
apoptosis and efferocytosis. A great example here is cell debris that must be removed to …

KLF14 alleviated breast cancer invasion and M2 macrophages polarization through modulating SOCS3/RhoA/Rock/STAT3 signaling

J Chu, XC Hu, CC Li, TY Li, HW Fan, GQ Jiang - Cellular signalling, 2022 - Elsevier
Purpose To study the functions and underlying network of KLF14 in breast cancer invasion
and tumor-associated macrophages (TAMs). Methods The expressions of gene or protein …

Unravelling the molecular mechanisms of prostate cancer evolution from genotype to phenotype

D Tong - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
Prostate cancer (PC) is the most frequently diagnosed cancer and the second leading cause
of cancer-related death in men in the Western society. Unfortunately, although the vast …

A review of the effects and molecular mechanisms of dimethylcurcumin (ASC‐J9) on androgen receptor‐related diseases

H Hu, H Zhou, D Xu - Chemical Biology & Drug Design, 2021 - Wiley Online Library
Abstract Dimethylcurcumin (ASC‐J9) is a curcumin analogue capable of inhibiting prostate
cancer cell proliferation. The mechanism is associated with the unique role of ASC‐J9 in …

S100a9 protects male lupus-prone NZBWF1 mice from disease development

LM Davison, AA Alberto, HA Dand, EJ Keller… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune disorder disproportionally affecting
women. A similar sex difference exists in the murine New Zealand Black/White hybrid model …

[HTML][HTML] Androgen-mediated anti-inflammatory cellular processes as therapeutic targets in lupus

JM Jones, TN Jørgensen - Frontiers in Immunology, 2020 - frontiersin.org
Systemic Lupus Erythematosus (SLE), among many other auto-immune diseases, is known
to be more prevalent in females than in males. This observation has served as the …

Hyperandrogenic environment regulates the function of ovarian granulosa cells by modulating macrophage polarization in PCOS

X Chen, L Hong, L Diao, T Yin… - American Journal of …, 2024 - Wiley Online Library
Background Polycystic ovary syndrome (PCOS) is a common endocrine‐metabolic disorder
characterized by oligo‐anovulation, hyperandrogenism, and polycystic ovaries, with …

[PDF][PDF] Androgen receptor inhibition alleviated inflammation in experimental autoimmune myocarditis by increasing autophagy in macrophages.

WH Ma, XG Zhang, LL Guo, JB Zhang… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: Experimental autoimmune myocarditis (EAM) is characterized by pronounced
macrophage infiltration, cardiac necrosis, and cardiac fibrosis. Our previous studies have …