Recent progress in machine learning approaches for predicting carcinogenicity in drug development
Introduction This review explores the transformative impact of machine learning (ML) on
carcinogenicity prediction within drug development. It discusses the historical context and …
carcinogenicity prediction within drug development. It discusses the historical context and …
[HTML][HTML] Gold nanoparticles attenuate the interferon-γ induced SOCS1 expression and activation of NF-κB p65/50 activity via modulation of microRNA-155-5p in triple …
A Farhana, A Alsrhani, N Rasheed… - Frontiers in …, 2023 - frontiersin.org
Objective Triple-negative breast cancer (TNBC) is a very aggressive form of cancer that
grows and spreads very fast and generally relapses. Therapeutic options of TNBC are …
grows and spreads very fast and generally relapses. Therapeutic options of TNBC are …
[HTML][HTML] Gold Nanoparticles Downregulate IL-6 Expression/Production by Upregulating microRNA-26a-5p and Deactivating the RelA and NF-κBp50 Transcription …
A Farhana, A Alsrhani, RS Alghsham, W Derafa… - International Journal of …, 2024 - mdpi.com
MicroRNAs (miRNAs) are involved in the modulation of pathogenic genes by binding to their
mRNA sequences'3′ untranslated regions (3′ UTR). Interleukin-6 (IL-6) is known to …
mRNA sequences'3′ untranslated regions (3′ UTR). Interleukin-6 (IL-6) is known to …
[HTML][HTML] Mitochondrial–Stem Cell Connection: Providing Additional Explanations for Understanding Cancer
P Martinez, I Baghli, G Gourjon, TN Seyfried - Metabolites, 2024 - mdpi.com
The cancer paradigm is generally based on the somatic mutation model, asserting that
cancer is a disease of genetic origin. The mitochondrial–stem cell connection (MSCC) …
cancer is a disease of genetic origin. The mitochondrial–stem cell connection (MSCC) …
Unraveling the Complexity of Immune Checkpoint Modulation in Gastrointestinal Malignancies
M Shoaib, HM Haseeb, K Bano… - Pak-Euro Journal of …, 2023 - readersinsight.net
Gastrointestinal cancers are accountable for the highest mortality rates on a global scale,
including gastric adenocarcinomas and hepatocellular carcinoma on a large scale. Tumor …
including gastric adenocarcinomas and hepatocellular carcinoma on a large scale. Tumor …
[PDF][PDF] Immunotherapy Influence On Human Body: Glycan Engineering Antibody-Based Cancer Treatments
KM Bakare, AM Nkeiruka, UO Matthew… - J Comm Med and Pub …, 2024 - academia.edu
Abstract Analysis of cells, soluble substances, and related tissues and cells that cooperate to
extend life continues to awaken researchers' curiosity. Because of its incredible complexity …
extend life continues to awaken researchers' curiosity. Because of its incredible complexity …
Repurposing mitochondrial-targeting anthelmintic agents with GLUT1 inhibitor BAY-876 for cancer therapy
TJ Schumacher, AV Iyer, J Rumbley, CT Ronayne… - bioRxiv, 2024 - biorxiv.org
Cancer cells alter their metabolic phenotypes with nutritional change. Single agent
approaches targeting mitochondrial metabolism in cancer have failed due to either dose …
approaches targeting mitochondrial metabolism in cancer have failed due to either dose …
[引用][C] Aisha Farhana1, Abdullah Alsrhani1, Naila Rasheed2, 3 and Zafar Rasheed4
N Yusuf, SM Aghaei-Zarch, S Shyamasundar… - 2023 - europepmc.org
Objective: Triple-negative breast cancer (TNBC) is a very aggressive form of cancer that
grows and spreads very fast and generally relapses. Therapeutic options of TNBC are …
grows and spreads very fast and generally relapses. Therapeutic options of TNBC are …